Abstract
A group of 25 children affected by different degrees of psychomotor retardation (severe (n=13); mild-moderate (n=12)) and symptoms suggesting gastro-oesophageal reflux (GOR) underwent oesophageal manometry and oesophageal pH monitoring. Of these patients, 21 (84%) were affected by GOR. In all children with severe brain damage and GOR (12/13), oesophageal manometry showed marked motility abnormalities that persisted after cure of GOR. In patients with minor retardation and GOR (9/12), oesophageal manometry showed normal motility or a less severe degree of oesophageal motor dysfunction which improved after curing the GOR. These results suggest that oesophageal motor dysfunction is a frequent occurrence in children affected by severe psychomotor retardation and GOR.
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Abbreviations
- GOR:
-
gastro-oesophageal reflux
- LOS:
-
lower oesophageal sphincter
- UOS:
-
upper oesophageal spincter
References
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Staiano, A., Cucchiara, S., Del Giudice, E. et al. Disorders of oesophageal motility in children with psychomotor retardation and gastro-oesophageal reflux. Eur J Pediatr 150, 638–641 (1991). https://doi.org/10.1007/BF02072624
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DOI: https://doi.org/10.1007/BF02072624