Skip to main content
Log in

Total body mineral mass measured with dual photon absorptiometry in healthy children

  • Growth/Development
  • Original Paper
  • Published:
European Journal of Pediatrics Aims and scope Submit manuscript

Abstract

Using dual photon absorptiometry, bone mineral content (BMC) and bone mineral density (BMD) of the total body and the lumbar spine were assessed in 97 healthy, Caucasian children aged 3–14 years. Excellent correlations were found between BMC and BMD on the one hand and age, body height and body weight on the other. No differences were found between boys and girls. There was a strong correlation between lumbar spine measurement as compared to those of the total body. Regression equations for total body and the different parts of the skeleton were calculated with either BMC or BMD as the dependent variable, and age, body height and body weight as independent variables. High variation coefficients were obtained in these multiple regressions, except for the head. For total body BMC and total body BMD, growth charts were constructed using Tanner and Whitehouse data on body height and body height and body weight.

The increase in total body mineral content is an important feature of normal growth. Normal data for BMC and BMD in childhood are essential for bone mineralistation abnormalities in paediatric patients.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Abbreviations

BA :

bone area

BMC :

bone mineral content

BMD :

bone mineral density

DPA :

dual photon absorptiometry

TBBMC :

total body BMC

TBBMD :

total body BMD

References

  1. Depriester JA, Cole TJ, Bishop NJ (1991) Bone growth and mineralisation in children aged 4–10 years. Bone Mineral 12: 57–65

    Article  Google Scholar 

  2. Dequeker J, Nijs J, Verstraeten A, Geusens P, Gevers G (1987) Genetic determinants of bone mineral content at the spine and the radius: a twin study. Bone 8: 207–209

    Article  PubMed  Google Scholar 

  3. De Schepper J, Derde MP, Van den Broeck M, Piepsz A, Jonckheer MH (1991) Normative data for lumbar spine bone mineral content in children: Influence of age, height, weight and pubertal stage. J Nucl Med 32: 216–220

    PubMed  Google Scholar 

  4. Geusens P, Dequeker J, Verstraeten A, Nijs J (1986) Age-, sex- and menopause-related changes of vertebral and peripheral bone: Population study using dual and single photon absorptiometry and radiogammametry. J Nucl Med 27: 1540–1549

    PubMed  Google Scholar 

  5. Gilsanz V, Varterasian M, Senac MO, Cann CE (1986) Quantitative spinal mineral analysis in children. Ann Radiol 29: 380–382

    PubMed  Google Scholar 

  6. Gilsanz V, Gibbens DT, Roe TF, Carlson M, Senac MO, Boechat MI, Huang HK, Schul EE, Libanati CR, Cann CC (1988) Vertebral bone density in children: effect of puberty. Radiology 166: 847–850

    PubMed  Google Scholar 

  7. Glastre C, Braillon P, Cochat P, Meunier PJ, Delmas PD (1990) Measurement of bone mineral content of the lumbar spine by dual energy X-ray absorptiometry in normal children: correlations with growth parameters. J Clin Endocrinol Metabol 70: 1330–1333

    Google Scholar 

  8. Hui SL, Johnston CC, Mazess RB (1985) Bone mass in normal children and young adults. Growth 49: 34–43

    PubMed  Google Scholar 

  9. Katzman DK, Bachrach LK, Varter DR, Marcus R (1991) Clinical and anthropometric correlates of bone mineral acquisition in healthy adolescent girls. J Clin Endocrinol Metabol 73: 1332–1339

    Google Scholar 

  10. Krolner B, Nielsen P (1980) Measurement of bone mineral content (BMC) of the lumbar spine. Theory and application of a new two dimensional dualphoton attenuation method. Scand J Clin Invest 40: 653–663

    PubMed  Google Scholar 

  11. Landin L, Nilsson BE (1981) Forearm bone mineral content in children. Normative data. Acta Paediatr Scand 70: 919–923

    PubMed  Google Scholar 

  12. Laraque D, Arena L, Karp J, Gruskay D (1990) Bone mineral content in black pre-schoolers: Normative data using single photon absorptiometry. Pediatr Radiol 20: 461–463

    PubMed  Google Scholar 

  13. Li JY, Specker BL, Ho ML, Tsang RC (1989) Bone mineral content in black and white children 1 to 6 years of age. Early appearance of race and sex differences. Am J Dis Child 143: 1346–1349

    PubMed  Google Scholar 

  14. Mazess RB, Cameron JR (1972) Growth of bone in school children: comparison of radiographic morphometry and photon absorptiometry. Growth 36: 77–92

    PubMed  Google Scholar 

  15. Mazess RB, Peppler WW, Chesney RW, Lange TA, Lindgren U, Smith E (1984) Total body and regional bone mineral by dual-photon absorptiometry in metabolic bone disease. Calcif Tissue Int 36: 8–13

    PubMed  Google Scholar 

  16. Mc Cormick DP, Ponder SW, Fawcett HD, Palmer JL (1991) Spinal bone mineral density in 335 normal and obese children and adolescents: Evidence for ethnic and sex differences. J Bone Min Res 6: 507–513

    Google Scholar 

  17. Miller JZ, Slemenda CW, Meany FJ, Reister TK, Hui S, Johnston CC (1991) The relationship of bone mineral density and anthropometric variables in healthy male and female children. Bone Mineral 14: 137–152

    Article  Google Scholar 

  18. Mimouni F, Tsang RC (1988) Bone mineral content: data analysis. J Pediatr 113: 178–180

    PubMed  Google Scholar 

  19. Peppler WW, Mazess RB (1981) Total body and lean body mass by dual photon absorptiometry. I. Theory and measurement procedure. Calcif Tissue Int 33: 353–359

    PubMed  Google Scholar 

  20. Pittard WB, Geddes KM, Sutherland SE, Miller MC, Hollis BW (1990) Longitudinal changes in bone mineral content in term and preterm infants. Am J Dis Child 144: 36–45

    PubMed  Google Scholar 

  21. Ponder SW, Mc Cormick DP, Fawcett HD, Palmer JL, Mc Kernan MG, Brouhard BM (1990) Spinal bone mineral density in children aged 5 through 11.99 years. Am J Dis Child 144: 1346–1348

    PubMed  Google Scholar 

  22. Southard RN, Morris JD, Mahan JD, Hayes JR, Torch MA, Sommer A, Zipf WB (1991) Bone mass in healthy children: measurement with quantitative DEXA. Radiology 179: 735–738

    PubMed  Google Scholar 

  23. Specker BL, Brazerol W, Tsang RC, Levin R, Searcy J, Steichen J (1987) Bone mineral content in children 1 to 6 years of age. Am J Dis Child 141: 343–344

    PubMed  Google Scholar 

  24. Steichen JJ, Steichen Asch PA, Tsang RC (1988) Bone mineral content in small infants by single photon absorptiometry: current methodologic issues. J Pediatr 113: 181–187

    PubMed  Google Scholar 

  25. Tanner JM, Whitehouse RH, Takahashi M (1966) Standards from birth to maturity for height, weight, height velocity; British children 1965. Arch Dis Child 41: 613–635

    PubMed  Google Scholar 

  26. Tison F, Ythier H, Lecouffe P, Rousseau J, Marchancise X (1990) Valeurs normales chez l'enfant du contenu mineral osseux mesuré par absorptiométrie biphotonique. Ann Pédiatr 37: 334–336

    Google Scholar 

  27. Vyhmeister NR, Linkhart TA, Hay S, Baylink DJ, Ghosh B (1987) Measurement of bone mineral content in the term and preterm infant. Am J Dis Child 141: 506–510

    PubMed  Google Scholar 

  28. Wahner HW, Dequeker JV (1988) A general overview. In: Dequeker JV, Geusens P, Wahner HW (eds) Bone mineral measurements by photon absorptiometry: methodological problems. Leuven University Press, Leuven pp 1–6

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Proesmans, W., Goos, G., Emma, F. et al. Total body mineral mass measured with dual photon absorptiometry in healthy children. Eur J Pediatr 153, 807–812 (1994). https://doi.org/10.1007/BF01972888

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01972888

Key words

Navigation