Abstract
Sjögren syndrome (SS) is a common disorder in adults and involves both glandular and extraglandular systems. We report here four cases of childhood SS complicated by chronic thyroiditis, interstitial nephritis or sweat gland inflammation. Additionally, in one of these cases, the central nervous system was involved. All of these complications are common in adult cases.
Similar content being viewed by others
Abbreviations
- dRTA :
-
distal renal tubular acidosis
- KCS :
-
keratoconjunctivitis sicca
- PSP :
-
phenolsulphophthalein
- s-GPT :
-
serum glucose pyruvate transaminase
- s-GOT :
-
serum glutamate oxalate transaminase
- SS :
-
Sjögren syndrome
References
Alexander EL (1986) Central nervous system (CNS) manifestation of primary Sjögren's syndrome; an overview. Scand J Rheumatol [Suppl] 61:161–165
Alexander EL, Ranzenbach MR, Kumar AJ, Kozachuk WE, Rosenbaum AE, Patronas N, Harley, JB Reichlin M (1994) Anti-Ro (SS-A) autoantibodies in central nervous system disease associated with Sjögren's syndrome (CNSSS): clinical, neuroimaging, and angiographic correlates. Neurology 44:899–908
Athreya BH, Norman ME, Myers AR, South MA (1977) Sjögren's syndrome in children. Pediatrics 59:931–938
Bloch KJ, Buchanan WW, Wohl MJ, Bunin JJ (1965) Sjögren's syndrome. A clinical, pathological and serological studies of 62 cases. Medicine 44:187–231
Chudwin DS, Daniels TE, Wara DW, Ammann AJ, Barrett DJ, Whitcher JP, Cowan MJ (1981) Spectrum of Sjögren's syndrome in children. J Pediatr 98:213–217
Deprettere AJ, Van Acker KJ, De Clerck LS, Docx MK, Stevens WJ, Van Bever HP (1988) Diagnosis of Sjögren's syndrome in children. Am J Dis Child 142:1185–1187
Epstein O, Thomas HC, Sherlock S (1980) Primary biliary cirrhosis is a dry gland syndrome with features of chronic graft-versus-host disease Lancet 1:1166–1168
Fox RI, Robinson CA, Curd JG, Kozin F, Howell FV (1986) Sjögren's syndrome; proposed criteria for classification. Arthritis Rheum 29:577–585
Fraga A, Gudiño J, Ramos-Niebro F, Alarcón-Segovia D (1978) Mixed connective tissue disease in childhood. Relationship with Sjögren's syndrome. Am J Dis Child 132:263–265
Franklin DJ, Smith RJH, Person DA, Pflugfelder SC (1986) Sjögren's syndrome in children. Otolaryngol Head Neck Surg 94:230–235
Mizuno Y, Hara T, Hatae K, Hirano T, Ueda K, Nakamura N, Mizoguchi Y (1989) Recurrent parotid gland enlargement as an initial manifestation of Sjö-gren's syndrome in children. Eur J Pediatr 148:414–416
Rosenberg AM, Dyck RF, George DM (1990) Intravenous pulse methylprednisolone for the treatment of a child with Sjögren's nephropathy. J Rheumatol 17:391–394
Shioji R, Furuyama T, Onodera S, Saito H, Ito H, Sasaki Y (1970) Sjögren's syndrome and renal tubular acidosis. Am J Med 48:456–463
Siamopoulou-Mavridou A, Drosos AA, Andropoulos AP (1989) Sjögren's syndrome in childhood; report of two cases. Eur J Pediatr 148:523–524
Talal N, Zisman E, Schur PH (1970) Renal tubular acidosis and immunologic factors in Sjbgren's syndrome. Arthritis Rheum 11:774–786
Talal N, Darphinee MJ, Dang H, Alexander SS, Hart DJ, Garry RF (1990) Detection of serum autoantibodies to retroviral protein in patients with primary Sjögren's syndrome (autoimmune exocrinopathy). Arthritis Rheum 33:774–781
Vermylen C, Meurant A, Claus D, Corms G (1985) Sjögren's syndrome in a child. Eur J Pediatr 144:266–269
Whaley K, Webb J, McAvoy BA, Hughes GRC, Lee P, MacSween RNM, Buchanan WW (1973) Sjögren's syndrome. 2. Clinical associations and immunological phenomena. Quart J Med 42:513–548
Whaley K, Alspaugh M (1985) Sjögren's syndrome. In: Kelley WN, Harris ED, Ruddy S, Sledge CL (eds). Textbook of rheumatology, 2nd edn. Saunders, Philadelphia, pp 956–973
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kobayashi, I., Furuta, H., Tame, A. et al. Complications of childhood Sjögren syndrome. Eur J Pediatr 155, 890–894 (1996). https://doi.org/10.1007/BF02282840
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02282840