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[18F]-Fluorodeoxyglucose-positron emission tomography findings in preterm infants with severe periventricular leukomalacia and hypsarrhythmia

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Abstract

Two preterm infants with extensive periventricular leukomalacia (PVL) were examined by [18F]-fluorodeoxyglucose-positron emission tomography (FDG-PET) at the corrected ages of 18 and 34 days. They showed similar clinical courses including oculoclonic seizure, hypsarrhythmia and severe mental retardation, in addition to spastic quadriplegia. FDG-PET study of these two infants with severe PVL disclosed poorly developed metabolic activity in the primary sensorimotor cortex, while the MRI images displayed only periventricular white matter lesions.

Conclusion Positron emission tomography may dis‐close cortical involvement in infants with severe periventricular leukomalacia.

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Authors and Affiliations

  1. Department of Paediatrics, Faculty of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606, Japan Tel: 81–075–751–3296, Fax: 81–075–752–2361, , , , , , JP

    Y. Higuchi, T. Maihara, H. Hattori & K. Furusho

  2. Department of Nuclear Medicine, Faculty of Medicine, Kyoto University, Kyoto, Japan, , , , , , JP

    H. Okazawa, K. Ishizu & Y. Yonekura

Authors
  1. Y. Higuchi
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  2. T. Maihara
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  3. H. Hattori
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  4. K. Furusho
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  5. H. Okazawa
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  6. K. Ishizu
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  7. Y. Yonekura
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Received: 23 March 1996 / Accepted: 10 August 1996

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Higuchi, Y., Maihara, T., Hattori, H. et al. [18F]-Fluorodeoxyglucose-positron emission tomography findings in preterm infants with severe periventricular leukomalacia and hypsarrhythmia. Eur J Pediatr 156, 236–238 (1997). https://doi.org/10.1007/s004310050591

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  • DOI: https://doi.org/10.1007/s004310050591

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