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The infectivity ofEncephalitozoon cuniculi in vivo and in vitro

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Abstract

The infectivity ofEncephalitozoon cuniculi grown in cell cultures was determined in cultured cells and in wild and domestic rabbits. The ratio of the total to tissue culture viable count was 1,300 (median of seven determinations). The mean ratio of intact spore count to total count, as determined by electron microscopy was 0.12. Although variation between infectivity experiments was large, the median animal infective dose contained 51 FFU (cell culture focus-forming units) for wild rabbits (Oryctolagus cuniculus) and 40 FFU for domestic rabbits. These two infectivities were not statistically different.

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Authors and Affiliations

  1. Commonwealth Serum Laboratories, Poplar Road, 3052, Parkville, Melbourne, Australia

    J. C. Cox, R. C. Hamilton & D. Pye

  2. Keith Turnbull Research Institute, 3199, Frankston, Australia

    J. W. Edmonds

Authors
  1. J. C. Cox
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  2. R. C. Hamilton
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  3. D. Pye
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  4. J. W. Edmonds
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Cox, J.C., Hamilton, R.C., Pye, D. et al. The infectivity ofEncephalitozoon cuniculi in vivo and in vitro. Z. Parasitenkd. 72, 65–72 (1986). https://doi.org/10.1007/BF00927735

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  • DOI: https://doi.org/10.1007/BF00927735

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