Skip to main content
SpringerLink
Log in

Coping with complexity: lessons from the mathematical sciences

  • Food for Thought
  • Published:
Human Genetics Aims and scope Submit manuscript

Abstract

I suggest five research paradigms fundamental in the mathematical sciences that seem relevant to the hunt for explanations of genetic susceptibility to complex diseases. I discuss a few ways in which these paradigms are, or are not, currently being followed in complex disease genetics. This essay is intended to provoke discussion and not to resolve any problems. It represents a written version of remarks that I made as “Discussant’’ at a session at the 1997 National Institutes of Health Research Festival.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

  1. National Human Genome Research Institute, National Institutes of Health, Suite 2000, 333 Cassell Drive, Baltimore, MD 21224, USA e-mail: schaffer@helix.nih.gov, Tel.: +1 410 550 7125, Fax: +1 410 550-7513, , , , , , TP

    Alejandro A. Schäffer

Authors
  1. Alejandro A. Schäffer
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schäffer, A. Coping with complexity: lessons from the mathematical sciences. Hum Genet 103, 5–10 (1998). https://doi.org/10.1007/s004390050775

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s004390050775

Keywords

Search

Navigation