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Ring chromosome 10 Associated with multiple congenital malformations

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Summary

A 46,XY,r(10) karyotype was found in lymphocytes and skin fibroblasts cultured from a 8-month-old male showing multiple malformations and severe mental retardation. A comparison of the clinical features observed in cases in which a 10 ring was identified by means of banding techniques has been also attempted.

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Authors and Affiliations

  1. 1a Clinica Ostetrica e Ginecologica, Unità di Medicina Preventiva Perinatale, Università di Milano, Via Commenda 12, Milano, Italy

    G. Simoni & L. Dalprà

  2. Istituto di Biologia Generale, Università di Milano, Italy

    F. Rossella

  3. Laboratorio di Anatomia e Istologia Patologica, Sez. di Citogenetica, Istituti Clinici di Perfezionamento, Milano, Italy

    G. Visconti

  4. 2a Clinica Pediatrica, Università di Milano, Italy

    C. Piria-Schwarz

Authors
  1. G. Simoni
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  2. F. Rossella
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  3. L. Dalprà
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  4. G. Visconti
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  5. C. Piria-Schwarz
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Simoni, G., Rossella, F., Dalprà, L. et al. Ring chromosome 10 Associated with multiple congenital malformations. Hum Genet 51, 117–121 (1979). https://doi.org/10.1007/BF00287164

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  • DOI: https://doi.org/10.1007/BF00287164

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