Summary
Using “new” techniques (malic acid thin layer agarose gel electrophoresis and/or isoelectric focusing), the polymorphism of the human red cell isozyme system esterase D (ESD) was shown to be extended. We report the gene frequencies observed among 312 unrelated Caucasian individuals living in the Düsseldorf area. The finding of a “new” allele at the ESD locus is also described.
This is a preview of subscription content, log in via an institution to check access.
References
Bär W, Häni M, Biedermann V (1984) Esterase D: simultaneous electrophoresis determination of the three common allozymes ESD (1,2,5). Electrophoresis 5:280–281
Bender K, Frank R (1974) Esterase D-polymorphismus: Darstellung in der Hochspannungselektrophorese und Mitteilung von Allelhäufigkeiten. Hum Genet 23:315–318
Berg K, Schwarzfischer F, Wischerath H (1976) Esterase D polymorphism. Description of the “new allele EsD4. Hum Genet 32:81–83
Eriksen B, Dissing J (1979) Human red cell esterase D polymorphism in Denmark and its application to paternity cases. Ref. 8. Int Tgg Ges. forens. Blutgruppenk, London
Henke J, Basler M (1984) Evidence for a “new” allele at the esterase D locus. Z Rechtsmed 92:35–37
Henke J, Schweitzer H, Bär W (1985) Elektrophoretische Darstellung der Produkte der Esterase-D-Allele ESD*1, EDS*2, EDS*5, und ESD*7. Ärztl Lab 31:123–124
Hopkinson DA, Mestriner MA, Cortner J, Harris H (1973) Esterase D: a new human polymorphism. Ann Hum Genet 27:119–137
Marks MP, Jenkins I, Nurse GT (1977) The red cell glutamic pyruvate transaminase, carbonic anhydrase I and II and esterase D polymorphism in the Ambo populations of South West Africa, with evidence for the existence of an EsD0 allele. Hum Genet 37:49–54
Martin W (1979) Neue Elektrophoresemethoden zur Darstellung von Serum- und Enzymopolymorphismen: technische Verbesserungen. Hinweise auf ein weiteres EsD-Allel. Ärztl Lab 25:65–67
Mukai S, Rapaport JM, Shields JA, Augsburger JJ, Dryja TP (1984) Linkage of genes for human esterase D and hereditary retinoblastoma. Am J Ophthalmol 97:681–685
Nishigaki I, Itoh T (1984) Isoelectric focusing studies of human red cells esterase D: evidence for polymorphic occurrence of a new allele EsD7 in Japanese. Hum Genet 66:92–95
Radam G, Strauch H, Martin W (1980) Der Phänotyp “Rügen” im Polymorphismus der Esterase D. Hinweis auf die Existenz eines neuen Allels (EsD6). Blut 40:337–341
Siege M, Schwehn B (1983) Polymorphismus des Esterase-D-Systems. Nachweis eines neuen Allels EsD7. Ärztl Lab 29:288–290
Sparkes RS, Murphree AL, Lingua RW, Sparkes MC, Field LL, Funderburk SJ, Benedict WF (1983) Gene for hereditary retinoblastoma assigned to human chromosome 13 by linkage to esterase D Science 219:971–973
Weidinger S, Gradl G, Cleve H, Schwarzfischer F (1985) Genetic study of red cell esterase D polymorphism by isoelectric focusing Abstracts 11th congress of the Soc. for forens. Hemogenetics Copenhagen.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Henke, J., Schweitzer, H., Bar, W. et al. Extended polymorphism of the human esterase D isozyme system: description of a “new” allele EsD*11. Hum Genet 73, 89–90 (1986). https://doi.org/10.1007/BF00292672
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF00292672