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Molecular characterization of ataxia telangiectasia T cell clones

III. Mapping the 14q32.1 distal breakpoint

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Summary

To delimit the 14q32.1 recurrent breakpoint of ataxia telangiectasia clones, we performed an in situ hybridization study with various probes located on the 14q32 band. We thus mapped this breakpoint between the D14S1 and Pi loci. Furthermore, an interstitial duplication including D14S1 and a part of the IgH locus was demonstrated on a t(14;14) clone.

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Stern, MH., Zhang, F., Thomas, G. et al. Molecular characterization of ataxia telangiectasia T cell clones. Hum Genet 81, 18–22 (1988). https://doi.org/10.1007/BF00283722

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  • DOI: https://doi.org/10.1007/BF00283722

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