Skip to main content
Log in

An informative MspI polymorphism detected at the D21S16 locus

  • Published:
Human Genetics Aims and scope Submit manuscript

Summary

A new RFLP is described at the D21S16 locus formerly linked to familial Alzheimer's disease.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Gardiner K, Watkins P, Münke M, Drabkin H, Jones C, Patterson D (1988) Partial physical map of chromosome 21. Somat Cell Mol Genet 14:623–638

    Google Scholar 

  • Nizetic D, Zehetner G, Monaco A, Craig A, Hoheisel J, Lennon G, Young B, Lehrach H (1989) Construction of high density cosmid reference libraries from human chromosome X and 21, analysis of clone order by the oligonucleotide fingerprinting technique. Am J Hum Genet 45:A154

    Google Scholar 

  • Stewart GD, Harris P, Galt J, Ferguson-Smith MA (1985) Cloned DNA probes regionally mapped to human chromosome 21 and their use in determining the origin of nondisjunction. Nucleic Acids Res 13:4125–4132

    Google Scholar 

  • StGeorge-Hyslop PH, Tanzi R, Polinsky RJ, Haines JL, Nee L, Watkins PC, Myers RH, Feldman RG, Pollen D, Drachman D, Growdon J, Bruni A, Foncin JF, Salmon D, Frommelt P, Amaducci L, Sorbi S, Piacentini S, Stewart GD, Hobbs WJ, Conneally PM, Gusella JF (1987) The genetic defect causing familial Alzheimer's disease maps on chromosome 21. Science 235:885–890

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Van Camp, G., Vandenberghe, A. & Van Broeckhoven, C. An informative MspI polymorphism detected at the D21S16 locus. Hum Genet 85, 140 (1990). https://doi.org/10.1007/BF00276344

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00276344

Keywords

Navigation