Summary
A new RFLP is described at the D21S16 locus formerly linked to familial Alzheimer's disease.
Similar content being viewed by others
References
Gardiner K, Watkins P, Münke M, Drabkin H, Jones C, Patterson D (1988) Partial physical map of chromosome 21. Somat Cell Mol Genet 14:623–638
Nizetic D, Zehetner G, Monaco A, Craig A, Hoheisel J, Lennon G, Young B, Lehrach H (1989) Construction of high density cosmid reference libraries from human chromosome X and 21, analysis of clone order by the oligonucleotide fingerprinting technique. Am J Hum Genet 45:A154
Stewart GD, Harris P, Galt J, Ferguson-Smith MA (1985) Cloned DNA probes regionally mapped to human chromosome 21 and their use in determining the origin of nondisjunction. Nucleic Acids Res 13:4125–4132
StGeorge-Hyslop PH, Tanzi R, Polinsky RJ, Haines JL, Nee L, Watkins PC, Myers RH, Feldman RG, Pollen D, Drachman D, Growdon J, Bruni A, Foncin JF, Salmon D, Frommelt P, Amaducci L, Sorbi S, Piacentini S, Stewart GD, Hobbs WJ, Conneally PM, Gusella JF (1987) The genetic defect causing familial Alzheimer's disease maps on chromosome 21. Science 235:885–890
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Van Camp, G., Vandenberghe, A. & Van Broeckhoven, C. An informative MspI polymorphism detected at the D21S16 locus. Hum Genet 85, 140 (1990). https://doi.org/10.1007/BF00276344
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00276344