Skip to main content
SpringerLink
Log in

Allelic variants of human calcitonin receptor in the Japanese population

  • Original investigation
  • Published:
Human Genetics Aims and scope Submit manuscript

Abstract

Evidence from cDNA cloning has shown that calcitonin receptors (CTRs) have seven potential transmembrane domains. In this study, structural analysis of CTRs from ten cultured human tumor cell lines and 117 human blood samples demonstrated allelic variants at the 1377th nucleotide in intracellular domain 4, expressing either proline or leucine as the 463rd amino acid. It was found that the variant with proline at this site was the more prevalent type of CTR among the Japanese population.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

  1. Second Department of Pathology, Wakayama Medical College, 27-Kyubancho Wakayama City, Wakayama, 640 Japan Tel.: +81 734-26-8315; Fax: +81 734-33-2053, , , , , , JP

    M. Nakamura, Zhi-qiang Zhang, Liang Shan, Tomoyuki Hisa, Toyoharu Yokoi & Kennichi Kakudo

  2. Department of Pediatrics, Wakayama Medical College Kihoku Hospital, Wakayama, 649-71 Japan, , , , , , JP

    Mitsuyo Sasaki

  3. Department of Pediatrics, Arita City Hospital, Wakayama, 649-03 Japan, , , , , , JP

    Ryuichi Tsukino

  4. Kaname Clinic, Wakayama, 647 Japan, , , , , , JP

    Akio Kaname

Authors
  1. M. Nakamura
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Zhi-qiang Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Liang Shan
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Tomoyuki Hisa
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Mitsuyo Sasaki
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Ryuichi Tsukino
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Toyoharu Yokoi
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Akio Kaname
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Kennichi Kakudo
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Received: 21 June 1996

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nakamura, M., Zhang, Zq., Shan, L. et al. Allelic variants of human calcitonin receptor in the Japanese population. Hum Genet 99, 38–41 (1996). https://doi.org/10.1007/s004390050307

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s004390050307

Keywords

Search

Navigation