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In vitro analysis of the cellular localization of luteinizing hormone releasing factor (LRF) in the basal hypothalamus of the rat

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Summary

Light and electron microscopic autoradiographic analysis of the medial basal hypothalamus of rat brains incubated for 30 and 60 minutes in tritiated luteinizing releasing factor (3H-LRF) revealed selective uptake in the form of silver grains over specialized ependyma (tanycytes) and perivascular glial cells in the palisade-contact zone of the median eminence. The functional capacity of tanycytes and glia are discussed in light of these data.

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Supported by U.S.P.H.S. Grants NS 08171 and AM 10002

U.S.P.H.S. Career Development Awardee K04 GM 70001

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Scott, D.E., Dudley, G.K., Knigge, K.M. et al. In vitro analysis of the cellular localization of luteinizing hormone releasing factor (LRF) in the basal hypothalamus of the rat. Cell Tissue Res. 149, 371–378 (1974). https://doi.org/10.1007/BF00226771

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