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A new membrane organelle in developing amphibian neurones

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Summary

Membrane specialisations have been found on neurones in embryos of the clawed toad Xenopus laevis. The specialisations have been called dense membrane knobs and consist of an outpushing of the plasma membrane with a slight increase in its density. The out-pushing forms a spherical knob with an amorphous dense core and a total diameter of 500 to 600 Å. The knobs are found on axons and dendrites both in the spinal cord and peripherally.

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References

  • Brightman, W. M., Reese, T. S.: Junctions between intimately apposed cell membranes in the vertebrate brain. J. Cell Biol. 40, 648–677 (1969)

    Google Scholar 

  • Bunge, M. B.: Fine structure of nerve fibres and growth cones of isolated sympathetic neurons in culture. J. Cell Biol. 56, 713–735 (1973)

    Google Scholar 

  • Hayes, B. P., Roberts, A.: Synaptic junction development in the spinal cord of an amphibian embryo: an electron microscope study. Z. Zellforsch. 137, 251–269 (1973)

    Google Scholar 

  • Hayes, B. P., Roberts, A.: The distribution of synapses along the spinal cord of an amphibian embryo: an electron microscope study of junction development. Cell and Tissue Res. (in press)

  • Heuser, J., Katz, B., Miledi, R.: Structural and functional changes of frog neuromuscular junctions in high calcium solutions. Proc. roy. Soc. B 178, 407–415 (1971)

    Google Scholar 

  • Lentz, T. L.: Fine structure of nerves on the regenerating limb of the newt Triturus. Amer. J. Anat. 121, 647–670 (1967)

    Google Scholar 

  • Nieuwkoop, P. D., Faber, J.: Normal tables of Xenopus laevis (Daudin). Amsterdam: North Holland Publishing Co. 1956

    Google Scholar 

  • Reynolds, E. S.: The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. J. Cell Biol. 17, 208–212 (1963)

    Google Scholar 

  • Skoff, R. P., Hamburger, V.: Fine structure of dendritic and axonal growth cones in embryonic chick spinal cord. J. comp. Neurol. 153, 107–148 (1974)

    Google Scholar 

  • Tennyson, V. M.: Fine structure of axon and growth cone of dorsal root neuroblast of rabbit embryo. J. Cell Biol. 44, 62–79 (1970)

    Google Scholar 

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Roberts, A., Hayes, B.P. A new membrane organelle in developing amphibian neurones. Cell Tissue Res. 154, 103–108 (1974). https://doi.org/10.1007/BF00221074

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  • DOI: https://doi.org/10.1007/BF00221074

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