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Changes in the fine structure of venous endothelium in the rabbit following adrenaline infusion

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Summary

The fine structure of the endothelium lining the femoral and mesenteric veins in the rabbit was examined following the infusion of concentrations of adrenaline varying from 0.5 to 5.0 μg/kg. Control animals were infused with saline.

Vesiculation of the endothelial cells was observed following each infusion of adrenaline, the effect being most marked with the highest dose used. It is suggested that this vesiculation may be associated with the release of antihaemophilic globulin and/or plasminogen activator from the endothelial cells.

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Authors and Affiliations

  1. University Department of Surgery, Hope Hospital, 6, Salford, England

    N. J. Griffiths & M. H. Irving

  2. Department of Anatomy, University of Manchester, Manchester, England

    J. S. Dixon

Authors
  1. N. J. Griffiths
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  2. M. H. Irving
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  3. J. S. Dixon
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Additional information

The authors wish to express their gratitude to Mrs. M. Woodford, Miss. G. Moore and Mr. R. Ellis for their skilful technical assistance

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Griffiths, N.J., Irving, M.H. & Dixon, J.S. Changes in the fine structure of venous endothelium in the rabbit following adrenaline infusion. Cell Tissue Res. 169, 123–128 (1976). https://doi.org/10.1007/BF00219312

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  • DOI: https://doi.org/10.1007/BF00219312

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