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Ultrastructure of pinealocytes of the cotton rat, Sigmodon hispidus

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Summary

Fine structural features of pinealocytes of cotton rats (Sigmodon hispidus) were examined. Golgi complexes, mitochondria, endoplasmic reticulum and polysomes are usual organelles seen in the perikaryonal cytoplasm of pinealocytes. Many non-granulated vesicles (40 to 80 nm in diameter) and a few granulated vesicles (about 100 nm in diameter) are associated with the Golgi cisternae. Occasionally, the cisternae contain granular materials. The perikaryonal cytoplasm of pinealocytes is characterized by the presence of inclusion bodies. These bodies are usually round in shape, not bounded by a limiting membrane and composed of fine granular or filamentous materials of high electron-opacity, which are similar in appearance to the substance seen in the nucleolonema. Pinealocyte processes, filled with abundant non-granulated vesicles and some granulated vesicles, are mainly found within the parenchyma and occasionally in perivascular spaces.

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References

  • Benson, B., Krasovich, M.: Circadian rhythm in the number of granulated vesicles in the pinealocytes of mice. Effects of sympathectomy and melatonin treatment. Cell Tissue Res. 184, 499–506 (1977)

    Google Scholar 

  • Ito, T., Matsushima, S.: Electron microscopic observations on the mouse pineal, with particular emphasis on its secretory nature. Arch. Histol. Jpn. 30, 1–15 (1968)

    Google Scholar 

  • Kappers, J., Ariëns: The mammalian pineal organ. J. Neuro-visc. Rel. Suppl. 9, 140–184 (1969)

    Google Scholar 

  • Kappers, J., Ariëns: The mammalian pineal gland, a survey. Acta Neurochir. 34, 109–149 (1976)

    Google Scholar 

  • Kawabata, I.: Electron microscopy of the rat hypothalamic neurosecretory system. II. Nucleolus-like inclusion bodies in the cytoplasm of neurosecretory cells. Arch. Histol. Jpn. 26, 101–113 (1965)

    Google Scholar 

  • Le Beux, Y.J.: An ultrastructural study of the neurosecretory cells of the medial vascular prechiasmatic gland, the preoptic recess and the anterior part of the suprachiasmatic area. I. Cytoplasmic inclusions resembling nucleoli. Z. Zellforsch. 114, 404–440 (1971)

    Google Scholar 

  • Le Beux, Y.J., Langelier, P., Poirier, L.J.: Further ultrastructural data on the cytoplasmic nucleolus resembling bodies or nematosomes. Their relationship with the subsynaptic web and a cytoplasmic filamentous network. Z. Zellforsch. 118, 147–155 (1971)

    Google Scholar 

  • Lin, H.-S., Hwang, B.-H., Tseng, C.-Y.: Fine structural changes in the hamster pineal gland after blinding and superior cervical ganglionectomy. Cell Tissue Res. 158, 285–299 (1975)

    Google Scholar 

  • Matsushima, S., Morisawa, Y.: Effects of acute cold exposure on the ultrastructure of the mouse pinealocyte. Cell Tissue Res. 195, 461–469 (1978)

    Google Scholar 

  • Matsushima, S., Reiter, R.J.: Comparative ultrastructural studies of the pineal gland of rodents. In: Ultrastructure of endocrine and reproductive organs, pp. 335–356 (M. Hess, ed.). New York: John Wiley and Sons, Inc. 1975

    Google Scholar 

  • Matsushima, S., Kachi, T., Mukai, S., Morisawa, Y.: Functional relationship between sympathetic nerves and pinealocytes in the mouse pineal: Quantitative electron microscopic observations. Arch. Histol. Jpn. Suppl. 40, 279–291 (1977)

    Google Scholar 

  • Pellegrino de Iraldi, A.: Granulated vesicles in the pineal gland of the mouse. Z. Zellforsch. 101, 408–418 (1969)

    Google Scholar 

  • Pévet, P., Kuyper, M.A.: The ultrastructure of pinealocytes in the golden mole (Amblysomus hottentotus) with special reference to the granular vesicles. Cell Tissue Res. 191, 39–56 (1978)

    Google Scholar 

  • Pévet, P., Kappers, J., Ariëns, Nevo, E.: The pineal gland of the mole-rat (Spalax ehrenbergi, Nehring). I. The fine structure of pinealocytes. Cell Tissue Res. 174, 1–24 (1976)

    Google Scholar 

  • Romijn, H.J.: Structure and innervation of the pineal gland of the rabbit, Oryctolagus cuniculus (L.) II. An electron microscopic investigation of the pinealocytes. Z. Zellforsch. 141, 545–560 (1973)

    Google Scholar 

  • Romijn, H.J.: The ultrastructure of the rabbit pineal gland after sympathectomy, parasympathectomy, continuous illumination, and continuous darkness. J. Neural Transm. 36, 183–194 (1975)

    Google Scholar 

  • Romijn, H.J.: The influence of some sympatholytic, parasympatholytic and serotonin-synthesis- inhibiting agents on the ultrastructure of the rabbit pineal organ. Cell Tissue Res. 167, 167–177 (1976)

    Google Scholar 

  • Romijn, H.J., Mud, M.T., Wolters, P.S.: Diurnal variations in number of Golgi-dense core vesicles in light pinealocytes of the rabbit. J. Neural Transm. 38, 231–237 (1976)

    Google Scholar 

  • Sheridan, M.N., Reiter, R.J.: The fine structure of the hamster pineal gland. Am. J. Anat. 122, 357–376 (1968)

    Google Scholar 

  • Shimizu, N., Ishii, S.: Electron-microscopic observations on nucleolar extrusion in nerve cells of the rat hypothalamus. Z. Zellforsch. 67, 367–372 (1965)

    Google Scholar 

  • Spurr, A.R.: A low viscosity epoxy resin embedding medium for electron microscopy. J. Ultrastruct. Res. 26, 31–43 (1969)

    Google Scholar 

  • Upson, R.H., Benson, B.: Effects of blinding on the ultrastructure of mouse pinealocytes with particular emphasis on the dense-cored vesicles. Cell Tissue Res. 183, 491–498 (1977)

    Google Scholar 

  • Upson, R.H., Benson, B., Satterfield, V.: Quantitation of ultrastructural changes in the mouse pineal in response to continuous illumination. Anat. Rec. 184, 311–324 (1976)

    Google Scholar 

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Supported in part by NSF grant no. PCM 77-05734 and NIH grant no. HD-10202 (Morphology Core)

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Matsushima, S., Morisawa, Y., Petterborg, L.J. et al. Ultrastructure of pinealocytes of the cotton rat, Sigmodon hispidus . Cell Tissue Res. 204, 407–416 (1979). https://doi.org/10.1007/BF00233652

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