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CRF-immunoreactive nerve fibers in the circumventricular organs of the monkey, Macaca fuscata

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Summary

The occurrence of CRF (corticotropin-releasing factor)-immunoreactive nerve fibers in the circumventricular organs of adult male monkeys, Macaca fuscata, was studied on serially sectioned brains, by means of the peroxidase-antiperoxidase technique in combination with a highly specific and sensitive CRF antiserum. CRF-containing nerve fibers were found in high concentrations in the infundibulum and, in addition, in small numbers in the posterior lobe, organum vasculosum laminae terminalis, subfornical organ, and area postrema; they were missing in the pineal body and the subcommissural organ. The CRF immunoreactive nerve fibers distributed in these organs were located in the proximity of the blood vessels.

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Supported by a grant (No. 56440022) from the Ministry of Education, Science, and Culture, Japan

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Kawata, M., Hashimoto, K., Takahara, J. et al. CRF-immunoreactive nerve fibers in the circumventricular organs of the monkey, Macaca fuscata . Cell Tissue Res. 232, 679–683 (1983). https://doi.org/10.1007/BF00216438

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  • DOI: https://doi.org/10.1007/BF00216438

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