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Fatal disseminated Nocardia farcinica infection in a renal transplant recipient

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Abstract 

Six years after a renal cadaver transplant, a 20-year-old girl developed multiple painful cutaneous abscesses and bilateral pneumonia secondary to Nocardia farcinica infection. Despite broad in vitro sensitivity to several antibiotic agents and aggressive medical treatment, the patient failed to respond and died after 10 weeks of therapy. We conclude that Nocardia farcinica is a very aggressive organism in immunocompromised patients and is often resistant to antimicrobial agents.

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Authors and Affiliations

  1. Division of Nephrology and Dialysis, Bambino Gesù Children Research Hospital, Piazza S.Onofrio 4, I-00165 Rome, Italy e-mail: rinaldi@opbg.net Tel.: +39-06-68592393, Fax: +39-06-68592602, , , , , , IT

    S. Rinaldi & G. Rizzoni

  2. Division of Infectious Diseases, Bambino Gesù Children Research Hospital, Rome, Italy, , , , , , IT

    P. D’Argenio

  3. Division of Microbiology, Bambino Gesù Children Research Hospital, Rome, Italy, , , , , , IT

    E. Fiscarelli

  4. Microbiology Institute, A.O. Ospedali Riuniti di Bergamo, Bergamo, Italy, , , , , , IT

    C. Farina

Authors
  1. S. Rinaldi
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  2. P. D’Argenio
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  3. E. Fiscarelli
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  4. C. Farina
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  5. G. Rizzoni
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Additional information

Received: 28 April 1999 / Revised: 16 July 1999 / Accepted: 22 July 1999

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Rinaldi, S., D’Argenio, P., Fiscarelli, E. et al. Fatal disseminated Nocardia farcinica infection in a renal transplant recipient. Pediatr Nephrol 14, 111–113 (2000). https://doi.org/10.1007/s004670050023

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  • DOI: https://doi.org/10.1007/s004670050023

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