Abstract
88 subjects (36 males and 52 females) affected by multiple sclerosis (MS), were studied with the CES-D and SRT tests for the evaluation of depressive reactions and neuroticism. Comparing the results with those of the control group, we found a significant score for depression and somatization in the MS patients, whereas the scores for anxiety and inadequacy were normal.
Sommario
Gli AA hanno eaminato 88 soggetti (36 maschi e 52 femmine) affetti da sclerosi multipla ai quali sono stati applicati i questionari del CES-D e SRT per la valutazione delle reazioni depressive e del nevroticismo. Dalla comparazione dei risultati con quelli del gruppo di controllo, emergono differenze statisticamente significative nella popolazione esaminata per quanto riguarda depressione e somatizzazione mentre i punteggi per ansia ed inadeguatezza risultano normali.
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References
Allison R.S., Millar J.H.D.:Prevalence of disseminated sclerosis in Northern Ireland. Ulster Med Journal, 23, suppl. 2. 5, 1954.
Baldwin M.V.:A clinico-experimental investigation into the psychologic aspects of multiple sclerosis. J. Nerv. Ment. Dis., 115:299–342, 1952.
Bender J.:Le modificazioni psichiche nella Sclerosi a placche. Dtsch. Z. Nervenheilkd. CLXIII 1950; 4–5:483–526. In: Bignami A. et al. Riv. Neurol. 31:240–268, 1961.
Braceland F.J., Giffin M.E.:The mental changes associated with multiple sclerosis. Res. Publ. Assoc. Nerv. Ment. Dis. 28:450–455, 1950.
Brain W.R.:Critical review: disseminated sclerosis. Q.J. Med., 23:343–391, 1930.
Brown S., Davis T.K.:The mental symptoms of multiple sclerosis. Arch. Neurol. Psychiatry, 7:629–634, 1922.
Canton G., Santonastaso P., Perini G.I., Pastorelli C., Vezzù L., Zamboni S., Gradenigo G.:Ipertensione e nevroticismo: uno studio controllato sulla reazione psicologica alla malattia. Riv. Sper. Fren., 1:81–92, 1982.
Colombo G., Favero S., Munari F., Iaia V.:L'ischemia cerebrale reversibile: reazioni psicologiche alla malattia. Riv. Pat. Nerv. Ment., 104:15–22, 1983.
Cottrell S.S., Wilson S.A.K.:The affective symptomatology of disseminated sclerosis. A study of 100 cases. J. Neurol. Psychopathol. 7:1–30, 1926.
Davison K., Bagley C.R.:Schizophrenia like-psychoses associated with organic disorders of the central nervous system: review of the literature. In: Herrington R.N., Ed., Current problems in Neuropsychiatry. Headly Brothers, Kent, England, 1969.
Fava G.A.:Versione italiana del CES-D per la valutazione degli stati depressivi. In: Canestreri R., Nuovi metodi in psicometria, Organizzazioni Speciali, Firenze, 87–93, 1982.
Fava G.A., Kellner R.:Versione italiana del Symptom Rating Test (S.R.T.) di Kellner e Sheffield. In: Canestreri R., Nuovi metodi in psicometria, Organizzazioni Speciali, Firenze, 33–40, 1982.
Fava G., Perini G.I., Santonastaso P., Veller-Fornasa C.:Life events and psychological distress in dermatologic disorders: psoriasis, chronic urticaria and fungal infections. Br. J. of Medical Psychology, 53:277–282, 1980.
Goodstein R.K., Farrell R.B.:Multiple sclerosis presenting as a depressive illness. Dis. Nerv. Sys. 38:127–131, 1977.
Kahana E., Leibowitz V., Alter M.:Cerebral multiple sclerosis. Neurology, 21:1170–1176, 1971.
Kellner R., Sheffield B.F.:A self-rating scale of distress. Psychological Medicine, 3:88–100, 1973.
Merskey H., Buhrich N.A.:Hysteria and organic brain disease. Br. J. Med. Psychol., 48:359–366, 1975.
Mur J., Kumpel G., Dostal S.:An anergic phase of disseminated sclerosis with psychiatric course. Confin. Neurol., 28:37–49, 1966.
Oppenheim (1896) quoted byO'Malley P.O.: In: Severe Mental Symptoms in disseminated sclerosis. J. Irish Med. Assoc., 55:115–127, 1966.
Pavan L., Pierri M.:Il malato di cuore e il suo medico. Il Pensiero Scientifico Editore, Roma, 1979.
Perini G.I., Fava G.A., Kellner R., Munari F., Fava M., Rossi N., Grandi S., Pasquali-Evangelisti L., Bernardi M., Zecchino F.:Validazione italiana del Symptom Rating Test (S.R.T.) di Kellner e Sheffield. In: Canestrari R., Nuovi metodi in psicometria, Organizzazioni Speciali, Firenze, 41–50, 1982.
Pierfederici A., Fava G.A., Munari F., Rossi N., Baldaro B., Pasquali-Evangelisti L., Grandi S., Bernardi M., Zecchino F.:Validazione italiana del CES-D per la misurazione della depressione. In: Canestreri R., Nuovi metodi in psicometria, Organizzazioni Speciali, Firenze, 95–103, 1982.
Pratt R.T.C.:An investigation of the psychiatric aspects of disseminated sclerosis. J. Neurol. Neurosurg. Psychiatry, 14:326–335, 1951.
Radloff L.S.:The CES-D scale. Applied Psychological Measurements, 1:385, 1977.
Santonastaso P., Canton G., Ambrosio G.B., Zamboni S.:Hypertension and neuroticism. Psychotherapy and Psychosomatics, 41:7–11, 1984.
Schneider P.B.:Psycgologie Médicale. Payot, Paris, 1969.
Seiffer H.:Ueber psychiche in besondere intelligenzstorungen bei Multipler Sklerose. Arch. Psychiatrie, 40:253–283, 1905.
Sugar C., Nadell R.:Mental symptoms in multiple sclerosis. A study of 28 cases with review of the literature. J. Nerv. Ment. Dis., 98:267–280, 1943.
Surridge D.:An investigation into some psychiatric aspects of multiple sclerosis. Brit. J. Psychiatry, 115:749–764, 1969.
Trimble M.R., Grant I.:Psychiatric aspects of multiple scleroris. In: Benson D.F., Blumer D., Eds. Psychiatric Aspects of Neurologic Disease, Vol. II, pp. 279–299, Grune and Stratton, New York, 1981.
Whitlock F.A., Siskind M.M.:Depression as a major symptom of multiple sclerosis. J. Neurol. Neurosurg. Psychiatry, 43:861–865, 1980.
Wilkes S.:Lectures on Diseases of the Nervous System. Churchill, London, 1878.
Young A.C., Saunders J., Ponsford J.R.:Mental change as an early feature of multiple sclerosis. J. Neurol. Neurosurg. Psychiatry, 39:1008–1013, 1976.
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Colombo, G., Armani, M., Ferruzza, E. et al. Depression and neuroticism in multiple sclerosis. Ital J Neuro Sci 9, 551–557 (1988). https://doi.org/10.1007/BF02337008
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DOI: https://doi.org/10.1007/BF02337008