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Studies of the effects of liquid holding on viability and mutation frequency in N-methyl-N′-nitro-N-nitrosoguanidine-treated halophiles

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Abstract

The capacities ofHalobacterium cutirubrum and a moderate halophile NRC 41227 to survive and recover from treatment with N-methyl-N′-nitro-N-nitrosoguanidine have been compared.Halobacterium cutirubrum is resistant to this chemical and its mutation frequency is only slightly affected, whereas NRC 41227 is highly sensitive and its mutation frequency is markedly increased. The chemically treated extreme halophile fully regains viability during liquid holding, in notable contrast to its known failure to recover from the effects of ultraviolet irradiation.

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Authors and Affiliations

  1. Department of Biochemistry, University of Ottawa, 40 Somerset St. E., K1N 9B4, Ottawa, Ontario, Canada

    Peter S. Fitt, Nishi Sharma & Nrityen Barua

Authors
  1. Peter S. Fitt
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  2. Nishi Sharma
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  3. Nrityen Barua
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Fitt, P.S., Sharma, N. & Barua, N. Studies of the effects of liquid holding on viability and mutation frequency in N-methyl-N′-nitro-N-nitrosoguanidine-treated halophiles. Current Microbiology 18, 87–91 (1989). https://doi.org/10.1007/BF01570830

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