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Microchemical investigation of medicinal plants. VI

Estimation of reserpine and rescinnamine inRauwolfia

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Summary

A procedure is described for determining the total contents of reserpine and rescinnamine inRauwolfia. It is based on the yellowish-green color produced by both alkaloids on treatment with sodium nitrite and sulfuric acid. Spectral studies have established the identity of the colored species which exhibit maximum absorption at 385 nm. The latter is not produced by deserpidine.

Zusammenfassung

Ein Verfahren zur Bestimmung des Gesamtgehaltes an Reserpin und Rescinnamin inRauwolfia wurde beschrieben. Es beruht auf der gelbgrünen Farbreaktion beider Alkaloide mit Natriumnitrit und Schwefelsäure. Spektrophotometrische Untersuchungen ergaben die Identität beider gefärbter Reaktionsprodukte, deren Absorptionsmaximum bei 385 nm liegt. Letzteres ist bei Deserpidin nicht feststellbar.

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References

  1. E. Schlittler et al., Ann. New York Acad. Sci.59, 1 (1954).

    Google Scholar 

  2. Association of Old-Style Doctors of Thailand, Textbook of Thai Pharma- cology (in Thai). Bangkok: Ampolpitaya. 1963.

  3. S. Pongboonrod, Thai Edible and Medicinal Plants (in Thai). Bangkok: Kasembanakit. 1965. p. 461.

    Google Scholar 

  4. H. Pötter andR. Voigt, Pharmazie21, 291 (1966).

    Google Scholar 

  5. E. Ullmann andH. Kassalitzky, Arch. Pharm.295, 37 (1962).

    Google Scholar 

  6. B. C. Bose andR. Vijayvargiya, J. Pharm. Pharmacol.11, 456 (1959).

    Google Scholar 

  7. W. A. Mannell andM. G. Allmark, Drug Standards24, 6 (1956).

    Google Scholar 

  8. E. H. Sakal andE. J. Merrill, J. Amer. Pharm. Ass.43, 709 (1954).

    Google Scholar 

  9. W. R. Maynard, Jr., J. Ass. Offic. Agric. Chem.41, 676 (1958).

    Google Scholar 

  10. E. Ragazzi andG. Veronese, Mikrochim. Acta [Wien]1965, 966.

  11. P. B. Sheth andM. B. Giaimo, J. Ass. Offic Agric. Chem.46, 448 (1963).

    Google Scholar 

  12. W. J. Mader, G. J. Papariello, andP. B. Sheth, J. Ass. Offic. Agric. Chem.45, 589 (1962).

    Google Scholar 

  13. W. J. Mader, R. P. Haycock, P. B. Sheth, R. J. Connoly, andP. M. Shapoe, J. Ass. Offic. Agric. Chem.44, 13 (1961).

    Google Scholar 

  14. I. M. Jakovljevic, J. M. Fose, andN. R. Kuzel, Analyt. Chemistry34, 410 (1962).

    Google Scholar 

  15. E. B. Dechene, J. Amer. Pharm. Ass.44, 657 (1955).

    Google Scholar 

  16. U. Rutkowska andK. Wojsa, Herba pol.12, 101 (1966).

    Google Scholar 

  17. R. P. Haycock, P. B. Sheth, andW. J. Mader, J. Amer. Pharm. Ass.48, 479 (1959).

    Google Scholar 

  18. E. Kahane andM. Kahane, Ann. pharm. Franc.16, 726 (1958).

    Google Scholar 

  19. P. F. G. Boon, J. Assoc. Publ. Analysts2, 44 (1964).

    Google Scholar 

  20. Z. Nowakowska, I. Wilczynska, andW. Zyzynski, Acta Polon. Pharm.21, 161 (1964).

    Google Scholar 

  21. O. Weis-Fogh, Arch. Pharm. Chem.67, 425 (1960).

    Google Scholar 

  22. R. P. Haycock, P. B. Sheth, R. J. Connolly, andW. J. Mader, J. Ass. Offic. Agric. Chem.42, 613 (1959).

    Google Scholar 

  23. A. W. M. Indemans, I. M. Jakovljevic, andJ. J. A. M. van der Langerijt, Pharm. Weekbl.94, 1 (1959).

    Google Scholar 

  24. D. Banes, J. Amer. Pharm. Ass.46, 601 (1957).

    Google Scholar 

  25. C. R. Szalkowski andW. J. Mader, J. Amer. Pharm. Ass.45, 613 (1956).

    Google Scholar 

  26. D. Banes, J. Wolff, H. O. Fallscher, andJ. Carol, J. Amer. Pharm. Ass.45, 708 (1956).

    Google Scholar 

  27. V. Scarselli, Boll. soc. Ital. biol. sper.34, 1132 (1958).

    Google Scholar 

  28. H. S. Chou, C. Y. Ku, C. L. Chin, C. Y. Chen, C. L. Hu, S. L. Lo, andH. K. Chao, Acta Pharm. Sin.13, 280 (1966).

    Google Scholar 

  29. W. Rutkowska andK. Wojsa, Biul. Inst. Roslin Leczniczych9, 192 (1963).

    Google Scholar 

  30. P. Laugel andM. Hasselmann, Chim. analytique44, 433 (1962).

    Google Scholar 

  31. E. A. De Felice, Experientia14, 159 (1958).

    Google Scholar 

  32. J. Reichelt, Českosl. Farmac.5, 516 (1956).

    Google Scholar 

  33. R. E. Booth, J. Amer. Pharm. Ass.44, 568 (1955).

    Google Scholar 

  34. H. Wunderlich, Pharm. Zentralh.96, 68 (1957).

    Google Scholar 

  35. J. E. Gardner andS. J. Dean, Drug Standards28, 50 (1960).

    Google Scholar 

  36. D. Banes, J. Amer. Pharm. Ass.44, 408 (1955).

    Google Scholar 

  37. N. Nakamura andT. Yoshida, Ann. Rep. Takeda Res. Lab.18, 25 (1959).

    Google Scholar 

  38. Z. Zung, Českosl. Farm.6, 299 (1957).

    Google Scholar 

  39. H. Kaneko, R. Fujimoto, K. Namba, andK. Hayashi, J. Pharm. Soc. Japan82, 1493 (1962).

    Google Scholar 

  40. M. M. Dhar andS. Bhattacharji, J. Sc. Ind. Res. B, India14, 276 (1955).

    Google Scholar 

  41. T. S. Ma andR. Roper, Mikrochim. Acta [Wien]1968, 170.

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Authors and Affiliations

  1. Contribution from the Department of Chemistry, City University of New York, USA

    W. J. McGahren, S. Chuntragool,  P. Trunphong & T. S. Ma

  2. Faculty of Science, Chiengmai University, Thailand

    W. J. McGahren, S. Chuntragool,  P. Trunphong & T. S. Ma

Authors
  1. W. J. McGahren
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  2. S. Chuntragool
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  3. P. Trunphong
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  4. T. S. Ma
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Additional information

For Part V see Mikrochim. Acta [Wien]1969, 225. Inquiries and requests for reprints of this series of papers should be addressed to Prof.T. S. Ma, Department of Chemistry, City University of New York, Brooklyn, N. Y. 11210, U. S. A.

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McGahren, W.J., Chuntragool, S., Trunphong, P. et al. Microchemical investigation of medicinal plants. VI. Mikrochim Acta 57, 1100–1106 (1969). https://doi.org/10.1007/BF01219255

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  • DOI: https://doi.org/10.1007/BF01219255

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