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Non-penetrating trauma to the carotid artery with secondary thrombosis and embolism: Treatment by Thrombolysin

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Summary

A case of partially occluding post-traumatic thrombosis of the internal carotid artery and secondary embolism of the middle cerebral artery is reported. The patient was treated with Thrombolysin with coincident resolution of clinical symptoms and signs and clearing of the lesions on arteriography. This may have been fortuitous.

The subject of traumatic carotid artery thrombosis is reviewed in detail, and its pathophysiology is discussed, especially in relation to facts known about occlusive vascular disease secondary to atherosclerosis and related embolie phenomena. Suggestions are made concerning the treatment of this condition, especially with regard to developing rational criteria for opening vascular beds through evaluation of collateral cerebral blood flow. The uses of microvascular surgical techniques and thrombolytic therapy are considered.

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  1. H. H. Kaufman M.D.

    Present address: Division of Neurosurgery, University of Texas Medical School, Texas Medical Center, 77030, Houston, TX, USA

Authors and Affiliations

  1. Division of Neurosurgery, University of Arizona Medical School, USA

    H. H. Kaufman M.D.

  2. Department of Radiology, University of Arizona Medical School, USA

    T. A. Lind

  3. Department of Surgery, University of Arizona Medical School, USA

    D. S. Clark

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Kaufman, H.H., Lind, T.A. & Clark, D.S. Non-penetrating trauma to the carotid artery with secondary thrombosis and embolism: Treatment by Thrombolysin. Acta neurochir 37, 219–244 (1977). https://doi.org/10.1007/BF01402128

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