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Effect of omental transposition to the brain on protein synthesis in experimental cerebral ischaemia

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Summary

Occlusion of the middle cerebral artery severely affects the uptake of labelled leucine into various subcellular fractions from rabbit brain. Previous transposition of pedicled omentum to the cerebral surface maintains to a large extent the protein synthetic activity of the brain following arterial occlusion. The role of the transposed omentum in providing an effective collateral circulation and minimizing the occurrence of irreversible ischaemic lesions is stressed.

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References

  1. Astrup, J., Symon, L., Branston, N. M., Lassen, N. A., Cortical evoked potential and extracellular K+ and H+ at critical levels of brain ischemia. Stroke8 (1977), 51–57.

    PubMed  Google Scholar 

  2. De Riu, P. L., Falzoi, A., Papavero, L., Rocca, A., Viale, G. L., Local cerebral blood flow in rabbits following omental transposition to the brain and subsequent middle cerebral artery occlusion. J. Microsurg. (in press).

  3. Goldsmith, H. S., Chen, W. F., Duckett, S., Brain vascularization by intact omentum. Arch. Surg.106 (1973), 695–698.

    PubMed  Google Scholar 

  4. Goldsmith, H. S., Duckett, S., Chen, W. F., Prevention of cerebral infarction in the dog by intact omentum. Amer. J. Surg.130 (1975), 317–320.

    PubMed  Google Scholar 

  5. Goldsmith, H. S., Duckett, S., Chen, W. F., Prevention of cerebral infarction in the monkey by omental transposition to the brain. Stroke9 (1978), 224–229.

    PubMed  Google Scholar 

  6. Goldsmith, H. S., Omental transposition to human brain (letter to the Editor). Stroke9 (1978), 272.

    Google Scholar 

  7. Little, J. R., Implanted device for middle cerebral artery occlusion in conscious cats. Stroke8 (1977), 258–260.

    PubMed  Google Scholar 

  8. Lowry, O. H., Rosebrough, N. J., Farr, A. L., Randall, R. J., Protein measurement with the Folin phenol reagent. J. Biol. Chem.193 (1951), 265–275.

    PubMed  Google Scholar 

  9. Yanagihara, T., Effect of anoxia on protein metabolism in subcellular fractions of rabbit brain. Stroke5 (1974), 226–229.

    PubMed  Google Scholar 

  10. Yanagihara, T., Cerebral ischemia in gerbils: differential vulnerability of protein, RNA, and lipid syntheses. Stroke7 (1976), 260–263.

    Google Scholar 

  11. Yanagihara, T., Experimental stroke in gerbils: correlation of clinical, pathological and electroencephalographic findings and protein synthesis. Stroke9 (1978), 155–159.

    PubMed  Google Scholar 

  12. Yaşargil, M. G., Yonekawa, Y., Denton, I., Piroth, D., Benes, I., Experimental intracranial transplantation of autogenic omentum majus. J. Neurosurg.40 (1974), 213–217.

    PubMed  Google Scholar 

  13. Yonekawa, Y., Yaşargil, M. G., Brain vascularization by transplanted omentum: a possible treatment of cerebral ischemia. Neurosurgery1 (1977), 256–259.

    PubMed  Google Scholar 

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Cucca, G.S., Papavero, L., Pau, A. et al. Effect of omental transposition to the brain on protein synthesis in experimental cerebral ischaemia. Acta neurochir 51, 253–257 (1980). https://doi.org/10.1007/BF01406752

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