Summary
Serum IgG, IgA, and IgM levels have been measured in patients with brain tumours. Only in astrocytomas have significant differences been found with respect to the other brain tumours. The specific elevation of IgM levels in astrocytoma grade III (X=313+36, n=4) and astrocytoma grade IV (X=671+ 146, n=4) in comparison with astrocytoma grade II (X=180, n=2) shows clear correlation with the malignancy of astrocytomas.
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Hekim, N., Sayin, E., Demirkaya, E. et al. Serum IgM level as an index of malignancy in brain tumours. Acta neurochir 59, 227–230 (1981). https://doi.org/10.1007/BF01406352
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DOI: https://doi.org/10.1007/BF01406352