Summary
One night's sleep deprivation (SD) increased the growth hormone (GH) response to clonidine (2 ug/kg iv) in 11 normal men (p < 0.005). This finding may indicate that SD enhances alpha-2 adrenergic receptor function or that the GH response to GH releasing factor is increased by SD.
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Lal, S., Thavundayil, J.X., Krishnan, B. et al. Effect of sleep deprivation on the growth hormone response to the alpha-2 adrenergic receptor agonist, clonidine, in normal subjects. J. Neural Transmission 104, 291–298 (1997). https://doi.org/10.1007/BF01273189
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DOI: https://doi.org/10.1007/BF01273189