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Inhibition of Borna disease virus replication by ribavirin in persistently infected cells

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Summary

Ribavirin at concentrations from 1 to 10 μg/ml exihibited inhibitory effects on transcription of Borna disease virus (BDV) in persistently infected cells. Our present study indicates that ribavirin is a candidate anti-BDV drug.

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Authors and Affiliations

  1. Laboratory of Public Health, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan, Japan

    T. Mizutani, H. Inagaki, K. Araki, H. Kariwa & I. Takashima

  2. Institute for Animal Experimentation, School of Medicine, Hokkaido University, Sapporo, Japan, Japan

    J. Arikawa

Authors
  1. T. Mizutani
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  2. H. Inagaki
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  3. K. Araki
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  4. H. Kariwa
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  5. J. Arikawa
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  6. I. Takashima
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Received April 3, 1998 Accepted May 14, 1998

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Mizutani, T., Inagaki, H., Araki, K. et al. Inhibition of Borna disease virus replication by ribavirin in persistently infected cells. Arch. Virol. 143, 2039–2044 (1998). https://doi.org/10.1007/s007050050440

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  • DOI: https://doi.org/10.1007/s007050050440

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