Summary
tRNA was extracted from uninfected and poliovirus infected HEp-2 cells. The aminoacyl tRNA synthetase was obtained from rat liver. Several aminoacyl tRNAs, prepared “in vitro” were analyzed on a MAK column. Arginyl tRNA is quantitatively modified at 20 minutes of infection. After 6 hours, the incorporation of serine into seryl tRNA increases. Valyl- and leucyl tRNA remain unaltered at both periods of infection.
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Yudelevich, S., Grado, C., Icekson, I. et al. Chromatographic analysis of aminoacyl tRNAs of poliovirus infected HEp-2 cells. Archiv f Virusforschung 44, 75–83 (1974). https://doi.org/10.1007/BF01250215
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DOI: https://doi.org/10.1007/BF01250215