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Sila-Analoga des Chlorphenoxamins und des Clofenetamins

Sila-Pharmaka, 2. Mitt.

Sila-analogues of chlorphenocamine and clofenetamine

Sila-pharmaca, 2

  • Anorganische, Struktur- und Physikalische Chemie
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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Abstract

Sila-analoguesA 2 andB 2 of two drugs from the benzhydryl ether class, chlorphenoxamine and clofenetamine, were synthesized for the first time by the steps shown in scheme 1. They and their precursors I–VI were characterized by their physical (Table 1) and chemical properties and their structures confirmed by n.m.r., mass and infrared spectrocopy (Tables 2–5). Their physiological effects were investigated and compared with those of the carbon analogues (Chapter 5).

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Authors and Affiliations

  1. Institut für Anorganische Chemie der Technischen Universität Braunschweig, Pockelsstraße 4, D-3300, Braunschweig, Bundesrepublik Deutschland

    Reinhold Tacke & Ulrich Wannagat

Authors
  1. Reinhold Tacke
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  2. Ulrich Wannagat
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Additional information

1. Mitt.:R. Tacke undU. Wannagat, Mh. Chem.106, 1005 (1975).

Mit Auszügen aus der DissertationR. Tacke, Techn. Univ. Braunschweig 1974.

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Tacke, R., Wannagat, U. Sila-Analoga des Chlorphenoxamins und des Clofenetamins. Monatshefte für Chemie 107, 111–123 (1976). https://doi.org/10.1007/BF00909088

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  • DOI: https://doi.org/10.1007/BF00909088

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