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Synthesen von Alkyl-bzw. Cycloalkylpyridinen und Naphthyridinen

Enaminoketones, XIII: syntheses of alkyl-, cycloalkylpyridines, resp., and naphthyridines

Beiträge zur Chemie der Enaminoketone, 13. Mitt.

  • Organische Chemie und Biochemie
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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Abstract

Condensation reactions of alkyl-and cycloalkylenaminoketones, resp. with cyanoacetamide, malononitrile and 2-amino-1-propene-1,1,3-tricarbonitrile (2) are investigated. Hydrolysis of dicyanomethylene substituted alkyl-dihydropyridines3 leads to 1,6-naphthyridines4 and5. With 2-morpholino-1-cyclohexenyl-1-ethanone (6) isoquinolines8 and9 are obtained. Condensation of 2-morpholinomethylene-cycloalkanones11 yields cycloalkanepyridines12 and13. 2-Morpholinomethylene-1,3-cyclohexanediones18 with malononitrile give the quinolinones20.

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Authors and Affiliations

  1. Institut für Organische Chemie, Abteilung für Organische Chemie I, Universität Graz, Heinrichstraße 28, A-8010, Graz, Österreich

    Hans Junek, Otto S. Wolfbeis, Hertha Sprintschnik & Herbert Wolny

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  1. Hans Junek
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  2. Otto S. Wolfbeis
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  3. Hertha Sprintschnik
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  4. Herbert Wolny
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Junek, H., Wolfbeis, O.S., Sprintschnik, H. et al. Synthesen von Alkyl-bzw. Cycloalkylpyridinen und Naphthyridinen. Monatshefte für Chemie 108, 689–702 (1977). https://doi.org/10.1007/BF00912814

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  • DOI: https://doi.org/10.1007/BF00912814

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