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Diels-Alder-Reaktionen von Vinylindolen mit Arin und 1,4-Benzochinonen: Neue potentielle DNA-Interkalatoren

Diels-Alder reactions of vinylindoles with aryne and 1,4-benzoquinones: New potential DNA intercalators

  • Organische Chemie Und Biochemie
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Summary

Diels-Alder reactions of 2- and 3-vinylindoles with aryne, 1,4-benzo- and 1,4-naphtho-quinone lead to new six-ring annellated carbazoles. Molecular modeling studies predict that the compounds with coplanar framework are able to intercalate with the B-DNA.

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Authors and Affiliations

  1. Institut für Pharmazie, Fachbereich Chemie und Pharmazie, Universität Mainz, D-W-6500, Mainz 1, Bundesrepublik Deutschland

    Ulf Pindur, Ludwig Pfeuffer, Manfred Eitel, Martina Rogge & Manfred Haber

Authors
  1. Ulf Pindur
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  2. Ludwig Pfeuffer
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  3. Manfred Eitel
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  4. Martina Rogge
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  5. Manfred Haber
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Pindur, U., Pfeuffer, L., Eitel, M. et al. Diels-Alder-Reaktionen von Vinylindolen mit Arin und 1,4-Benzochinonen: Neue potentielle DNA-Interkalatoren. Monatsh Chem 122, 291–298 (1991). https://doi.org/10.1007/BF00810830

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  • DOI: https://doi.org/10.1007/BF00810830

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