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Relapse of multiple sclerosis following acute allergic reactions to plasma during plasmapheresis

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Summary

In a small pilot study of plasmapheresis in chronic progressive multiple sclerosis, two patients suffered relapses following an acute allergic reaction to plasma. It is suggested that allergic reactions may have played a role in the exacerbation and recommended that fresh frozen plasma be avoided in therapeutic trials for multiple sclerosis.

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Authors and Affiliations

  1. Department of Neurology and Hemapheresis Unit, Hadassah University Hospital and The Hebrew University Medical School, Jerusalem, Israel

    I. Wirguin & O. Abramsky

  2. Department of Haematology, Hadassah University Hospital and The Hebrew University Medical School, Jerusalem, Israel

    E. Shinar

Authors
  1. I. Wirguin
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  2. E. Shinar
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  3. O. Abramsky
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Wirguin, I., Shinar, E. & Abramsky, O. Relapse of multiple sclerosis following acute allergic reactions to plasma during plasmapheresis. J Neurol 236, 62–63 (1989). https://doi.org/10.1007/BF00314223

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  • DOI: https://doi.org/10.1007/BF00314223

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