Skip to main content
SpringerLink
Log in

A method for the determination of some organophosphorus insecticides in human serum

  • Originals
  • Published:
Chromatographia Aims and scope Submit manuscript

Summary

A simple and rapid method for the determination of organophosphorus insecticides in serum of poisoned patients is described. The compounds are extracted with benzene and the extraction residue is gas chromatographed on a glass capillary column with alkali flame ionisation detection. Concentrations from 2 ng cm−3 can be determined. As an example, results of the analysis of serum samples of three patients, poisoned with parathion and methylparation, are given.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. D. Grob, Anticholinesterase intoxication in man and its treatment; in Handbuch der experimentellen Pharmakologie XV, p. 989. Springer Verlag, Göttingen-Heidelberg, 1963.

    Google Scholar 

  2. M. F. Craumer, Bull. Environ. Contam. Toxicol.5, 329 (1970).

    Google Scholar 

  3. G. Boelcke, Arch. für Pharmakol.266, 298 (1970).

    CAS  Google Scholar 

  4. G. Boelcke, Arch. Toxikol.26, 161 (1970).

    CAS  Google Scholar 

  5. N. C. Jain, C. R. Fontan andP. L. Kirk, J. Pharm. Pharmacol.17, 362 (1965).

    CAS  Google Scholar 

  6. R. A. Vulkovich, A. J. Triolo andJ. M. Coon, J. Agr. Food Chem.17, 1190 (1969).

    Google Scholar 

  7. J. Bäulmer andS. Rippenstein, Arch. Toxikol.25, 57 (1969).

    Google Scholar 

  8. S. Okonek andH. Kilbinger, Arch. Toxicol.32, 97 (1974).

    Article  CAS  Google Scholar 

  9. K. Harzer andR. Barchet, Arch. Toxicol.34, 47 (1975).

    Article  CAS  Google Scholar 

Download references

Author information

Author notes

  1. M. De Potter

    Present address: Laboratory of Organic Chemistry, State University of Ghent, Krijgslaan 271-S4, B-9000, Ghent, Belgium

  2. R. Muller

    Present address: Department of Organic Chemistry, State University of Mons, B-7000, Mons, Belgium

Authors and Affiliations

  1. Laboratory of Medical Toxicology, Technical Division of the Army, Vilvoorde

    M. De Potter, R. Muller & J. Willems

  2. J. F. and C. Heymans Institute of Pharmacology, University of Ghent Medical School, De Pintelaan 135, B-9000, Ghent, Belgium

    M. De Potter, R. Muller & J. Willems

Authors
  1. M. De Potter
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. Muller
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. Willems
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

De Potter, M., Muller, R. & Willems, J. A method for the determination of some organophosphorus insecticides in human serum. Chromatographia 11, 220–222 (1978). https://doi.org/10.1007/BF02302397

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02302397

Keywords

Search

Navigation