Skip to main content
SpringerLink
Log in

Chromatographic behaviour of acids on macro-porous-polystyrene gels

  • Originals
  • Published:
Chromatographia Aims and scope Submit manuscript

Summary

The retention behaviour of aromatic acids was examined in a reversed-phase mode liquid chromatography. Macro porous styrene-divinylbenzene copolymers were selected on the basis of their chemical stability throughout the entire pH range.

The effect of addition of a hydrophobic ion in the eluent and that of an ion-exchange group on the packing were discussed in relation with the hydrophobicity and the dissociation constant of solutes.

The maximum capacity ratios of the acids on apolystyrene gel are linearly related with the hydrophobicity. The prediction of the retention time of aromatic acids could be possible by combination of their hydrophobicity and their dissociation constants.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. S. Mori, Anal. Chem.,50, 745 (1978).

    Google Scholar 

  2. D. M. Ordemann, H. F. Walton, Anal. Chem.,48, 1728 (1976).

    Google Scholar 

  3. T. Hanai, H. F. Walton, Anal. Chem.,49, 764 (1977).

    Google Scholar 

  4. T. Hanai, H. Hatano ed., “Application of high spced liquid chromatography”, Nankodo, Tokyo, Japan (1976) p. 23.

    Google Scholar 

  5. H. Takahagi, S. Seno, J. Chromatogr. Sci.,12, 507 (1974).

    Google Scholar 

  6. A. Nakae, G. Muto, J. Chromatogr.,120, 47 (1976).

    Google Scholar 

  7. D. J. Pietrzyk, Chi-Hung Chu, Anal. Chem.,49, 757 (1976).

    Google Scholar 

  8. M. Popl, V. Dolansky, J. Coupek, J. Chromatogr.,130, 195 (1977).

    Google Scholar 

  9. L. M. Jahangir, L. Olsson, O. Samuelson, Talanta22, 973 (1975).

    Google Scholar 

  10. G. Goldstein, J. Chromatogr.,129, 61 (1976).

    Google Scholar 

  11. M. Uchida, T. Tanimura, J. Chromatogr.,138, 17 (1977).

    Google Scholar 

  12. T. Hanai, H. F. Walton, J. D. Navratil, D. Warren, J. Chromatogr.,155, 261 (1978).

    Google Scholar 

  13. D. J. Pietrzyk, E. P. Kroeff, T. D. Rotsch, Anal. Chem.,50, 497 (1978).

    Google Scholar 

  14. T. D. Rotsch, R. J. Snyder, D. J. Pietrzyk, J. Chromatogr. Sci.,17, 339 (1979).

    Google Scholar 

  15. K. Aramiki, T. Hanal, H. F. Walton, Anal. Chem.,52, 1963 (1980).

    Google Scholar 

  16. T. Hanai, K. C. Tran, J. Hubert, J. HRC & CC,4, 454 (1981).

    Google Scholar 

  17. A. Leo, C. Hansch, D. Elkins, Chemical Reviews,71, 525 (1979).

    Google Scholar 

  18. R. F. Rekker, “The Hydrophobic Fragmental Constant”, Elsevier Sci. Publ. Com, Amsterdam (1977).

    Google Scholar 

  19. J. M. McCall, J. Med. Chem.,18, 549 (1975).

    Google Scholar 

  20. M. S. Mirreless, S. T. Moulton, C. T. Murphy, P. J. Tayler, J. Med. Chem.,19, 615 (1976).

    Google Scholar 

  21. D. Henry, J. H. Block, J. L. Anderson, G. R. Carson, J. Med. Chem.,19, 619 (1976).

    Google Scholar 

  22. N. Tanaka, E. R. Thornton, J. Am. Chem. Soc.,99, 7300 (1977).

    Google Scholar 

  23. K. Miyake, H. Terada, J. Chromatogr.,157, 386 (1978).

    Google Scholar 

  24. G. L. Biagi, A. M. Barbaro, M. C. Guera, G. Hakin, G. C. Solaini, P. A. Borea, J. Chromatogr.,177, 35 (1979).

    Google Scholar 

  25. R. M. Carlson, R. E. Carlson, H. L. Kopperman, J. Chromatogr.,107, 219 (1975).

    Google Scholar 

  26. I. Molnar, C. Horvath, J. Chromatogr.,142, 623 (1977).

    Google Scholar 

  27. N. Tanaka, H. Goodell, B. L. Karger J. Chromatogr.,158, 233 (1978).

    Google Scholar 

  28. J. K. Baker, P. O. Rauls, R. F. Borne, J. Med. Chem.,22, 1301 (1979).

    Google Scholar 

  29. T. Hanal, Chromatogr.,12, 77 (1979).

    Google Scholar 

  30. T. Hanai, M. D'Amboise, J. Liquid Chromatogr.,5, 229 (1982).

    Google Scholar 

  31. T. Hanai, J. Hubert, 6th FACSS Meeting, Philadelphia, September (1979).

  32. S. N. Deming, M. L. H. Turoff, Anal. Chem.,50, 546 (1978).

    Google Scholar 

  33. J. L. Van de Venne, J. J. H. M. Hendrikx, R. S. Keelder, J. Chromatogr.,167, 1 (1978).

    Google Scholar 

  34. Handbook of Chemistry and Physics 45th Edition, The Chemical Rubber Co., Cleveland (1964) D77.

  35. Merek Index 8th Edition, Merck Co., Inc., Rahway, USA (1968).

  36. R. P. W. Scott, P. Kucera, J. Chromatogr.,175, 51 (1979).

    Google Scholar 

  37. A. Tilley-Melin, Y. Sakemark, K.-G. Wahland, G. Schill, Anal. Chem.,51, 976 (1979).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Département de Chimie, Université de Montréal, Succ. A., C.P. 6210, H3c 3V1, Montréal, Québec, Canada

    T. Hanai & J. Hubert

Authors
  1. T. Hanai
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Hubert
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hanai, T., Hubert, J. Chromatographic behaviour of acids on macro-porous-polystyrene gels. Chromatographia 17, 633–639 (1983). https://doi.org/10.1007/BF02261948

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02261948

Key Words

Search

Navigation