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Theoretical models for electrodialytic sample treatment in trace analysis by liquid chromatography

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Summary

Basic considerations for analyte enrichment and recovery obtainable by electrodialysis as a sample treatment method are given. Equations are derived which describe the dependence of the concentration profiles of ionic compounds on the electric field strength in a set-up with stagnant donor and acceptor solutions. It is shown that analyte recovery increases when less ion-selective membranes are used in the electrodialysis cell. Computer models are used to estimate the analyte enrichment for a flowing donor (sample) and a stagnant acceptor phase. About 10-fold enrichment can be obtained in an electrodialytic sample treatment system within 20 min under maximum current conditions. A compromise has to be found between analyte recovery and the donor (sample) flow rate.

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References

  1. A. Kollrep and A. Wohl, Ger. Pat 136, 670 (1901).

  2. P. H. Prausnitz andJ. Reitstötter, Elektrophoresis, Elektrosmose, Elektrodialyse, Steinkopff, Dresden and Leipzig, 1931.

    Google Scholar 

  3. N. Tsunakawa, Chem. Pharm. Bull.19, 1164 (1971).

    Google Scholar 

  4. N. Tsunakawa, Chem. Pharm. Bull.19, 2579 (1971).

    PubMed  Google Scholar 

  5. N. Tsunakawa, Chem. Pharm. Bull.19, 2585 (1971).

    PubMed  Google Scholar 

  6. J. A. Cox, R. Carlson, Anal. Chim. Acta130, 313 (1981).

    Article  Google Scholar 

  7. M. W. F. Nielen, R. W. Frei, U. A. Th. Brinkman, in R. W. Frei and K. Zech (Eds.), “Selective Sample Handling and Detection in High-Performance Liquid Chromatography”, Part A, (J. Chromatogr. Library, Vol. 39A), Elsevier, Amsterdam, 1987, p. 5–80.

    Google Scholar 

  8. W. Th. Kok, Chromatographia24, 442 (1987).

    Google Scholar 

  9. W. Th. Kok, K.-P. Hupe, R. W. Frei, J. Chromatogr.436, 421 (1988).

    Article  Google Scholar 

  10. A. J. J. Debets, R. W. Frei, K.-P. Hupe, W. Th. Kok, J. Chromatogr.465, 315 (1989).

    PubMed  Google Scholar 

  11. A. J. J. Debets, K.-P. Hupe, U. A. Th. Brinkman, W. Th. Kok, Chromatographia29, 217 (1990).

    Google Scholar 

  12. D. C. Turnell, J. D. H. Cooper, J. Chromatogr.395, 613 (1987).

    Article  PubMed  Google Scholar 

  13. D. C. Turnell, J. D. H. Cooper, B. Green, F. Verillon, J. Chromatogr.456, 53 (1987).

    Google Scholar 

  14. U. R. Tjaden, E. A. Bruijn, R. A. M. van der Hoeven, C. Jol, J. van der Greef, H. Lingeman, J. Chromatogr.420, 53 (1987).

    PubMed  Google Scholar 

  15. M. M. L. Aerts, W. M. J. Beek, U. A. Th. Brinkman, J. Chromatogr.435, 97 (1988).

    Article  PubMed  Google Scholar 

  16. M. M. L. Aerts, W. M. J. Beek, U. A. Th. Brinkman, J. Chromatogr.500, 453 (1990).

    Article  PubMed  Google Scholar 

  17. N. C. van de Merbel, J. M. Teule, H. Lingeman, U. A. Th. Brinkman, J. Pharm. Biomed. Anal.10, 225 (1992).

    Article  PubMed  Google Scholar 

  18. P. R. Haddad, S. Laksana, R. G. Simons, J. Chromatogr.640, 135 (1993).

    Article  Google Scholar 

  19. A. J. J. Debets, W. Th. Kok, K.-P. Hupe, U. A. Th. Brinkman, Chromatographia30, 361 (1990).

    Google Scholar 

  20. A. J. J. Debets, K.-P. Hupe, W. Th. Kok, U. A. Th. Brinkman, J. Chromatogr.600, 163, (1992).

    Article  Google Scholar 

  21. R. Aris, Proc. Roy. Soc. London, Ser. A235, 67 (1956).

    Google Scholar 

  22. W. Th. Kok, U. A. Th. Brinkman, R. W. Frei, Anal. Chim. Acta162, 19 (1984).

    Article  Google Scholar 

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Authors and Affiliations

  1. N. V. Organon, AKZO NOBEL, P.O. Box 20, 5340 BH, Oss, The Netherlands

    A. J. J. Debets

  2. Department of Analytical Chemistry, Free University, de Boelelaan 1083, 1081 HV, Amsterdam, The Netherlands

    P. v. Wier, K. -P. Hupe & U. A. Th. Brinkman

  3. Laboratory for Analytical Chemistry, University of Amsterdam, Nieuwe Achtergracht 166, 1018 WV, Amsterdam, The Netherlands

    W. Th. Kok

Authors
  1. A. J. J. Debets
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  2. P. v. Wier
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  3. K. -P. Hupe
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  4. U. A. Th. Brinkman
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  5. W. Th. Kok
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Debets, A.J.J., v. Wier, P., Hupe, K.P. et al. Theoretical models for electrodialytic sample treatment in trace analysis by liquid chromatography. Chromatographia 39, 460–468 (1994). https://doi.org/10.1007/BF02278763

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  • DOI: https://doi.org/10.1007/BF02278763

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