Synthesis and characterization of a photoaffinity probe possessing biotinyl and azidobenzoyl moieties for IP-3-affiniated protein

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Abstract

A myo-inositol 1,4,5-tris(phosphate) analogue bearing p-azidobenzoyl and biotinyl moieties has been prepared and shown to act as a photoaffinity probe for myo-inositol 1,4,5-tris(phosphate) 5-phosphatase.

An inositol analogue, 3 has been synthesized and characterized.

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References (16)

  • M. Hirata et al.

    Nature

    (1985)
  • F.M. Finn et al.

    Biochemistry

    (1985)
  • L. Moroder et al.

    Hoppe-Seyler's Z. Physiol. Chem.

    (1976)
  • M. Hiratra et al.

    Biochem. Biophys. Res. Commun.

    (1990)
  • M.J. Berridge

    Ann. Rev. Biochem.

    (1987)
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