205Bi/206Bi cyclotron production from Pb-isotopes for absorption studies in humans

https://doi.org/10.1016/0969-8043(93)90100-OGet rights and content

Abstract

Pb(p, xn) thick target excitation functions were measured in the energy range 10–38 MeV in order to optimize the production of isotopically pure radiobismuth from natPb, 206Pb, and 207Pb. Additionally, the decay of Po-isotopes from deuteron irradiation of natural bismuth (209Bi) was exploited for radiobismuth production. 205Bi was produced from 206Pb at 20 MeV with only 2% of 206Bi at 4 weeks post irradiation. Bismuth compounds as used in the treatment of peptic ulcer were labeled with 205Bi for absorption studies in animals and subjects.

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