Adaptive assay of radioactive pulmonary aerosols with an external detector

https://doi.org/10.1016/0883-2889(90)90165-DGet rights and content

Abstract

The accuracy of the assay of radioactive pulmonary aerosols is influenced by the spatial distribution of the aerosol in the lungs. In general, there is considerable uncertainty in the spatial distribution of the aerosol beginning a few months after inhalation. This paper develops an adaptive approach for optimizing the assay of non-uniform spatial distributions of pulmonary aerosols. An adaptive assay is one in which the design of the assay system is modified during operation in response to measurements obtained on-line. Experimental results are presented which compare the performance of an adaptive assay with that of the standard measurement procedure. We study the assay of 241Am distributed in the lungs of a Lawrence Livermore realistic phantom using a NaICsI Phoswich detector.

References (10)

  • Y. Ben-Haim

    The Assay of Spatially Random Material

    (1985)
  • R.V. Hogg et al.

    Introduction to Mathematical Statistics

    (1970)
  • Y. Laichter et al.

    External Measurement of 239Pu Contamination in Human Lungs with a NaICsI Phoswich Detector

  • J.F. McShane et al.

    Pulmonary distribution of inhaled 239PuO2 in dogs

  • D. Newton et al.

    The Livermore phantom as a calibration standard in the assessment of plutonium in lungs

There are more references available in the full text version of this article.
View full text
Copyright © 1990 Published by Elsevier Ltd.