Calcium resorption from bone in a human studied by 41Ca tracing

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Abstract

We are investigating long- and short-term processes that involve the resorption of the bone calcium in the human body, using accelerator mass spectrometry of 41Ca (T12 = 104000 years). The evolution of an injected dose of 41Ca has been followed over 900 days by measurements in urine and serum. The 41 Ca/Ca isotopic ratio rapidly decreased after injection and after about 100 days, reached a quasi-steady state of 1.5 × 10−11. Variations in this level would signal a change in rates of calcium resorption from the bone.

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