Communication
Fractionation by lectin affinity chromatography indicates that the glycosylation of most ribonucleases in human viscera and body fluids is organ specific

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Abstract

The behavior of ribonucleases extracted from various human viscera in five lectin-Sepharose columns shows that almost all contain carbohydrates and that there are organ-specific differences in the structure of these carbohydrates.

References (19)

  • H. Sierakowska et al.
  • I.G. Renner et al.

    Gastroenterology

    (1978)
  • A.L. Warshaw et al.

    Amer. J. Surg

    (1980)
  • J.L. Weickmann et al.

    J. Biol. Chem

    (1982)
  • K.K. Reddi

    Biochem. Biophys. Res. Commun

    (1977)
  • J.U. Baenziger et al.

    J. Biol. Chem

    (1979)
  • K. Yamashita et al.

    J. Biol. Chem

    (1985)
  • K. Kornfeld et al.

    J. Biol. Chem

    (1981)
  • V.P. Bhavanandan et al.

    J. Biol. Chem

    (1979)
There are more references available in the full text version of this article.

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This work has been supported by a Grant-in-Aid for Developmental Scientific Research from the Ministry of Education, Science and Culture of Japan.

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