Biochemical and Biophysical Research Communications
Volume 205, Issue 2, 15 December 1994, Pages 1445-1451
Regular ArticleHepatocyte Growth Factor Region Specifically Stimulates Gastrointestinal Epithelial Growth in Primary Culture
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2011, Journal of Surgical ResearchCitation Excerpt :HGF was first identified in 1984 as a stimulant for hepatocyte DNA synthesis in rats [48]. However, after further investigation, its expression was detected outside of the liver in several organs, including the small intestine [49, 50]. In cell culture models, HGF was found to stimulate the proliferation and migration of intestinal epithelial cells and to promote tubular cell formation and growth [33].
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