Biochemical and Biophysical Research Communications
Volume 125, Issue 1, 30 November 1984, Pages 90-96
Human leukemia K562 cells: Relationship between hemin-mediated erythroid induction, cell proliferation and expression of c-abl and c-myc oncogenes
References (26)
- et al.
Cell
(1984) - et al.
Cell
(1984) - et al.
Cell
(1983) - et al.
Biochem.Biophys.Res.Comm.
(1984) - et al.
Blood
(1975) - et al.
Cell Differentiation
(1984) - et al.
Cell Differentiation
(1983) - et al.
J.Biol.Chem.
(1982) - et al.
Cell
(1980) - et al.
Blood
(1981)
FEBS Letters
(1982)
Nature
(1984)
Ann.Rev.Biochem.
(1983)
Cited by (17)
High-level embryonic globin production with efficient erythroid differentiation from a K562 erythroleukemia cell line
2018, Experimental HematologyCitation Excerpt :Interestingly, hemin was not required for high-level hemoglobin production in our erythroid differentiation protocol for K562 cells (Fig. 3). Hemin is thought to interfere with cell proliferation with a reduction of BCR/ABL gene expression, resulting in erythroid differentiation of K562 cells [7,27]. The combination of reagents in our protocol might be sufficient for a reduction of BCR/ABL gene (by imatinib) and cell proliferation (by imatinib and rapamycin) to induce erythroid differentiation of K562 cells.
ABL oncogene expression during erythroleukemia cell differentiation
1991, Leukemia ResearchEffect of erythroid differentiation factor on erythroid differentiation and proliferation of K-562 cells
1990, Biochemical and Biophysical Research CommunicationsBreakpoint zone of bcr in chronic myelogenous leukemia does not correlate with disease phase or prognosis
1988, Cancer Genetics and CytogeneticsPh positive CML cell lines
1987, Bailliere's Clinical Haematology
Copyright © 1984 Published by Elsevier Inc.