Journal of Fermentation and Bioengineering
On-line monitoring of cell concentrations by dielectric measurements
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Practical monitoring technologies for cells and substrates in biomanufacturing
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2020, Biochemical Engineering JournalCitation Excerpt :These results showed the ability of capacitance to track online the growth of A. terreus biomass. It is a new application of impedimetry as previously it was applied for biomass measurement of bacteria [34,38], fungi [23], cancerous cells, plant cells [39], and microalgae [40]. Kim et al. proved low effects of electrode polarization in high frequency for two gold electrode systems [34].
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2017, Chemical Engineering ScienceCitation Excerpt :The online biomass estimation based on carbon balancing was already applied for the µ-control of penicillin processes (Mou and Cooney, 1983a,b). In situ biomass measurements applied for filamentous organisms were fluorescence probes (Haack et al., 2007) and dielectric spectroscopy (Fehrenbach et al., 1992; Mishima et al., 1991; Neves et al., 2000; Sarra et al., 1996). Fluorescence probes were found to be not applicable for penicillin-producing cultures in complex media, as changes in the medium composition influence fluorescence.
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2014, Sensors and Actuators, B: ChemicalCitation Excerpt :Within the frequency range studied in that work, the dielectric relaxation involves the dipolar (rotational) polarization, which depends on the molecular structure of the material. The dielectric constant is due to the β-relaxation induced by polar groups on the side chains of SA [48,50]. This relaxation with a secondary mechanism is associated with a dipole component such as polar side chains of SA, namely –COO− groups [50].
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