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Aurora kinases dawn as cancer drug targets

Nature Medicine volume 10, pages 234–235 (2004)Cite this article

A new anticancer compound interferes with aurora kinases, regulators of mitosis. We can now hope for the biology of these kinases to inform clinical trials (pages 262–267).

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Figure 1: Chromosomal passengers in anaphase.

Mar Carmena, Richard Adams and William Earnshaw

Figure 2: Pharmacology of mitosis.

Debbie Maizels

References

  1. Harrington, E.A. et al. Nat. Med. 10, 262–267 (2004).

    Article  CAS  Google Scholar 

  2. Carmena, M. & Earnshaw, W.C. Nat. Rev. Mol. Cell Biol. 4, 842–854 (2003).

    Article  CAS  Google Scholar 

  3. Hauf, S. et al. J. Cell Biol. 161, 281–294 (2003).

    Article  CAS  Google Scholar 

  4. Ditchfield, C. et al. J. Cell Biol. 161, 267–280 (2003).

    Article  CAS  Google Scholar 

  5. Kapoor, T.M., Mayer, T.U., Coughlin, M.L. & Mitchison, T.J. J. Cell Biol. 150, 975–988 (2000).

    Article  CAS  Google Scholar 

  6. Johnson, R.K. et al. Proc. Am. Assoc. Cancer Res. 43, 269 (2002).

    Google Scholar 

  7. Johnson, J.I. et al. Br. J. Cancer 84, 1424–1431 (2001).

    Article  CAS  Google Scholar 

  8. Baguley, B.C. & Marshall, E.S. Eur. J. Cancer (in the press).

  9. Kuh, H.J., Jang, S.H., Wientjes, M.G. & Au, J.L.-S. J. Phamacol. Exp. Ther. 293, 761–770 (2000).

    CAS  Google Scholar 

  10. Dancey, J. & Sausville, E.A. Nat. Rev. Drug Discov. 2, 296–313 (2003).

    Article  CAS  Google Scholar 

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  1. Developmental Therapeutics Program, National Cancer Institute, Rockville, 20852, Maryland, USA

    Edward A Sausville

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  1. Edward A Sausville
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Sausville, E. Aurora kinases dawn as cancer drug targets. Nat Med 10, 234–235 (2004). https://doi.org/10.1038/nm0304-234

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