Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Effects of Atractyloside and Oligomycin on Magnesium-stimulated Adenosine Triphosphatase and on Adenosine Triphosphate-induced Contraction of Swollen Mitochondria

Nature volume 196, pages 578–580 (1962)Cite this article

Abstract

IN previous reports1 it was shown that atractyloside inhibits the energy-transfer reactions of oxidative phosphorylation in a manner similar to that of the antibiotic oligomycin2–4.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Bruni, A., and Contessa, A. R., Nature, 191, 818 (1961). Bruni, A., Contessa, A. R., and Luciani, S., Biochim. Biophys. Acta, 60, 301 (1962).

    Article  ADS  CAS  Google Scholar 

  2. Lardy, H. A., Johnson, D., and McMurray, W. C., Arch. Biochem. Biophys., 78, 587 (1958).

    Article  CAS  PubMed  Google Scholar 

  3. Huijing, F., and Slater, E. C., J. Biochem, (Tokyo), 49, 493 (1961).

    Article  CAS  PubMed  Google Scholar 

  4. Lardy, H. A., IUB/IUBS Symp. Biological Structure and Function, Stockholm, 2, 265 (Academic Press, 1960).

    Google Scholar 

  5. Hogeboom, G., Methods in Enzymology, 1, 16 (Academic Press, New York, 1955).

    Book  Google Scholar 

  6. Lehninger, A. L., J. Biol. Chem., 234, 2187 (1959); J. Biol. Chem., 234, 2465 (1959).

    CAS  PubMed  Google Scholar 

  7. Cooper, C., and Lehninger, A. L., J. Biol. Chem., 224, 561 (1957).

    CAS  PubMed  Google Scholar 

  8. Krebs, H. A., and Hems, R., Biochim. Biophys. Acta, 12, 172 (1953).

    Article  CAS  PubMed  Google Scholar 

  9. Cerletti, P., Ipata, P. L., and Siliprandi, N., Anal. Chim. Acta, 16 548 (1957).

    Article  CAS  Google Scholar 

  10. Cooper, C., and Kulka, R. G., J. Biol. Chem., 236, 2351 (1961).

    CAS  PubMed  Google Scholar 

Download references

Author information

Author notes

  1. S. LUCIANI: Fellow of the Consiglio Nazionale delle Ricerche.

Authors and Affiliations

  1. Pharmacological Institute, University of Padova, Italy

    A. BRUNI & S. LUCIANI

Authors
  1. A. BRUNI
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. LUCIANI
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

BRUNI, A., LUCIANI, S. Effects of Atractyloside and Oligomycin on Magnesium-stimulated Adenosine Triphosphatase and on Adenosine Triphosphate-induced Contraction of Swollen Mitochondria. Nature 196, 578–580 (1962). https://doi.org/10.1038/196578a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/196578a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing