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Labelling of Proteins with Cellulose-reactive Dyes

Abstract

IN 1923 azo dyes containing a cyanuric halide grouping were introduced by Ciba1. In recent years, the practical application of similar reactive compounds possessing a triazine chloride radical has been extended considerably2,3. Dyes of this type have the following type of structure: where ‘Dye —SO3H’ represents the sulphonated chromophor (azo, anthraquinone, phthalocyanine, etc.) and X stands for another chlorine atom or for an inactive radical. On the fibre, the halogen atom of the dye molecule reacts with the hydroxyl group of the cellulose molecule forming a covalent bond. Reactive dyes of the above type are marketed by Imperial Chemical Industries, Ltd., and by Ciba.

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References

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HESS, R., PEARSE, A. Labelling of Proteins with Cellulose-reactive Dyes. Nature 183, 260–261 (1959). https://doi.org/10.1038/183260a0

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