Abstract
INVESTIGATION of rat and mouse liver prepared by solvent substitution1,2 with 1 per cent mercuric chloride in absolute methanol has shown that a considerable portion of the cytoplasmic ribonucleic acid compounds combine with mercury. The nucleic acid compounds of the nucleus do not appear to combine with mercury under the experimental conditions used, that is, cooling to −190° C. and exposing to solvent at −65° C. for 48 hr. and then warming to room temperature. It is considered likely, though not conclusively proved, that the mercury has access to the nuclei during the solvent substitution.
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BELL, L. Sulphydryl Groups and Ribonucleic Acid. Nature 182, 1088–1089 (1958). https://doi.org/10.1038/1821088a0
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DOI: https://doi.org/10.1038/1821088a0
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