Abstract
In a previous communication1 it was shown that β-glucuronidase in liver or kidney rises following administration of toxic agents to mice, depending upon the organ or organs affected. It was suggested that a rise in this enzyme is associated with tissue repair rather than the damage itself. This view is confirmed by results for kidney following administration of mercuric nitrate or chloroform to male mice. In each case, the rise in the enzyme did not occur in the early stages of poisoning, but was seen when repair was well advanced.
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Kerr, L. M. H., and Levvy, G. A., Nature, 160, 463 (1947).
Fishman, W. H., and Fishman, L. W., J. Biol. Chem., 152, 487 (1944).
Fishman, W. H., Science, 105, 646 (1947).
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KERR, L., LEVVY, G. & CAMPBELL, J. β-Glucuronidase and Tissue Proliferation. Nature 160, 572 (1947). https://doi.org/10.1038/160572a0
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DOI: https://doi.org/10.1038/160572a0
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