Abstract
Serra, Guarini, Guidetti, Maisin and Deckers1 recently suggested the serological utilization of bovine foot and mouth disease (FMD) virus RNA as the antigenic component in the complement fixation reaction for identification of blood sera of carriers of malignant tumours. Fresh human blood serum shows, in the presence of RNA as antigen, a negative serological reaction with more or less intense haemolysis in 85 per cent of cases of malignant tumour; but it shows a positive serological reaction, without haemolysis, in 97 per cent of cases of young and normal people without malignant tumours, and in 83.5 per cent of these cases when the individual is suffering from other diseases.
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References
Serra, A., Guarini, G., Guidetti, E., Maisin, J., and Deckers, C., Nature, 206, 1264 (1965).
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GUIDETTI, E., SERRA, A., GUARINI, G. et al. Quantitative Evaluation of Immunological Reactivity of Carriers of Malignant Tumours against Foot and Mouth Disease Virus RNA by the Complement Fixation Reaction. Nature 212, 624–626 (1966). https://doi.org/10.1038/212624a0
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DOI: https://doi.org/10.1038/212624a0
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