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Autoradiographic studies on the experimental pulmonary fibrosis of rats after H3-proline injection

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Zusammenfassung

Mit einer 2-, 4-, 8- und 16-Wochenbehandlung wurde bei Ratten experimentell eine Lungenfibrose durch SiO2 verursacht. Später wurde i.p. H3-Prolin injiziert und durch Autoradiographie die pulmonale Fibrose bewertet. In den Pneumokoniose-Herden wurde die Radioaktivität mit der Zeit am intensivsten, wobei die höchste Aktivität in den Kollagenfasern gemessen wurde.

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Authors and Affiliations

  1. The 2nd Department of Internal Medicine, Nara Medical University, Nara, Japan

    Z. Horai, M. Kaneda, S. Kasahara, K. Shimizu, K. Yamamoto, T. Okuyama & T. Sugimoto

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  1. Z. Horai
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  2. M. Kaneda
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  3. S. Kasahara
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  4. K. Shimizu
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  5. K. Yamamoto
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  6. T. Okuyama
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  7. T. Sugimoto
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Horai, Z., Kaneda, M., Kasahara, S. et al. Autoradiographic studies on the experimental pulmonary fibrosis of rats after H3-proline injection. Experientia 28, 42–43 (1972). https://doi.org/10.1007/BF01928254

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  • DOI: https://doi.org/10.1007/BF01928254

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