Skip to main content
SpringerLink
Log in

Spinal cord tissue cultures-a model for autoradiographic studies on uptake of putative neurotransmitters such as glycine and GABA

  • Specialia
  • Published:
Experientia Aims and scope Submit manuscript

Zusammenfassung

Autoradiographische Untersuchungen haben gezeigt, dass3H-Glycin und3H-GABA in kultivierte Neurone und Gliazellen des Rückenmarks der Ratte aufgenommen werden. Aus unseren licht- und elektronenmikroskopischen Befunden geht hervor, dass die Nervengewebskultur ein geeignetes Versuchsmodell für Aufnahme und zelluläre Lokalisation von Überträgersubstanzen ist.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. T. Hökfelt andÅ. Ljungdahl, Brain Res.22, 391 (1970).

    Article  PubMed  Google Scholar 

  2. T. Hökfelt andÅ. Ljungdahl, Brain Res.32, 189 (1971).

    Article  PubMed  Google Scholar 

  3. T. Hökfelt andÅ. Ljungdahl, inHistochemistry of Nervous Transmission (Ed.O. Eränkö; Elsevier Publ. Comp., Amsterdam, London, New York); Progr. Brain Res.34, 87 (1971).

    Google Scholar 

  4. T. Hökfelt andÅ. Ljungdáhl, Exp. Brain Res.14, 354 (1972).

    Article  PubMed  Google Scholar 

  5. T. Hökfelt andÅ. Ljungdahl, inStudies on Neurotransmitters at the Synaptic Level (Eds.L. L. Iversen andE. Costa, Raven Press, New York) (1972); Adv. Biochem. Psychopharmac., in press.

    Google Scholar 

  6. F. E. Bloom andL. L. Iversen, Nature, Lond.229, 628 (1971).

    Article  CAS  PubMed  Google Scholar 

  7. L. L. Iversen andF. E. Bloom, Brain Res.41, 131 (1972).

    Article  CAS  PubMed  Google Scholar 

  8. F. Schon andL. L. Iversen, Brain Res.42, 503 (1972).

    Article  CAS  PubMed  Google Scholar 

  9. A. J. Matus andM. E. Dennison, Brain Res.32, 195 (1971).

    Article  CAS  PubMed  Google Scholar 

  10. L. Hösli andE. Hösli, Brain Res.45, 612 (1972).

    Article  PubMed  Google Scholar 

  11. T. Hökfelt, Z. Zellforsch.91, 1 (1968).

    Article  PubMed  Google Scholar 

  12. M. M. Murray, inHandbook of Neurochemistry (Ed.A. Lajtha; Plenum Press, New York, London 1971), p. 373.

    Google Scholar 

  13. L. Descarries, J. Microsc.6, 313 (1967).

    Google Scholar 

  14. E. Hösli andL. Hösli, Brain Res.30, 193 (1971).

    Article  PubMed  Google Scholar 

  15. J. H. Luft, J. biophys. biochem. Cytol.9, 409 (1961).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. E. S. Reynolds, J. Cell Biol.17, 208 (1963).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. L. G. Caro andR. P. van Tubergen, J. Cell Biol.15, 173 (1962).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  18. O. L. Miller Jr., G. E. Stone andD. M. Prescott, J. Cell Biol.23, 654 (1964).

    Article  PubMed  PubMed Central  Google Scholar 

  19. T. Nagata andT. Nawa, Histochemie7, 370 (1966).

    Article  CAS  PubMed  Google Scholar 

  20. J. R. Wolff, E. Hösli andL. Hösli, Brain Res.32, 198 (1971).

    Article  CAS  PubMed  Google Scholar 

  21. D. R. Curtis, L. Hösli, G. A. R. Johnston andI. H. Johnston, Expl. Brain Res.5, 235 (1968).

    Article  CAS  Google Scholar 

  22. R. Werman, R. A. Davidoff andM. H. Aprison, J. Neurophysiol.31, 81 (1968).

    Article  CAS  PubMed  Google Scholar 

  23. K. Krnjević andS. Schwartz, Expl. Brain Res.3, 320 (1967).

    Article  Google Scholar 

  24. K. Obata, M. Ito, R. Ochi andN. Sato, Expl. Brain Res.4, 43 (1967).

    Article  CAS  Google Scholar 

  25. D. R. Curtis andJ. M. Crawford, A. Rev. Pharmac.9, 209 (1969).

    Article  CAS  Google Scholar 

  26. D. R. Curtis, A. W. Duggan, D. Felix andG. A. R. Johnston, Brain Res.32, 69 (1971).

    Article  CAS  PubMed  Google Scholar 

  27. G. ten Bruggencate andI. Egnberg, Brain Res.25, 431 (1971).

    Article  PubMed  Google Scholar 

  28. L. L. Iversen andM. J. Neal, J. Neurochem.15, 1141 (1968).

    Article  CAS  PubMed  Google Scholar 

  29. J. M. Hopkin andM. J. Neal, Br. J. Pharmac.40, 136 P (1968).

    Google Scholar 

  30. J. M. Neal andH. G. Pickles, Nature, Lond.223, 679 (1969).

    Article  Google Scholar 

  31. Å. Ljungdahl andT. Hökfelt, in preparation.

  32. We would like to thank Dr.H. P. von Hahn and MissV. Steinmann for carrying out the perchloric acid extractions.

  33. L. Hösli, P. F. Andrès andE. Hösli, Brain Res.34, 399 (1971).

    Article  PubMed  Google Scholar 

  34. I. R. Faeder andM. M. Salpeter, J. Cell Biol.46, 300 (1970).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  35. P. M. Orkand andE. A. Kravitz, J. Cell Biol.49, 75 (1971).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  36. Acknowledgments: This study was supported by grants No. B72-14 X-2887-3B and No. B72-14.P-3662-02B) from the Swedish Medical Research Council and by grants from Karolinska Institutets Forskningsfonder, Ollie och Elof Ericssons Stiftelse, Stiftelsen skillful technical assistance of Mrs.W. Hiort and MissA.-C. Swenson is gratefully acknowledged.

Download references

Author information

Authors and Affiliations

  1. Department of Neurophysiology, Neurological Clinic of the University of Basel, CH-4051, Basel, Switzerland

    E. Hösli, Å. Ljungdahl, T. Hökfelt & L. Hösli

  2. Department of Histology, Karolinska Institutet, S-104 01, Stockholm 60, Sweden

    E. Hösli, Å. Ljungdahl, T. Hökfelt & L. Hösli

Authors
  1. E. Hösli
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Å. Ljungdahl
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. T. Hökfelt
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. L. Hösli
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hösli, E., Ljungdahl, Å., Hökfelt, T. et al. Spinal cord tissue cultures-a model for autoradiographic studies on uptake of putative neurotransmitters such as glycine and GABA. Experientia 28, 1342–1344 (1972). https://doi.org/10.1007/BF01965334

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01965334

Keywords

Search

Navigation