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Zentrale vegetative LSD-Effekte

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Summary

d-Lysergic acid diethylamide (LSD 25) produces in rabbits a syndrome consisting of hyperthermia, hyperglycemia, mydriasis, pilomotor activation, cardiac acceleration etc. Analysis of these effects leads to the assumption of an increased sympathetic discharge induced by the central nervous action of LSD 25. Comparison of LSD 25 and reserpine shows opposite characteristics of these two drugs not only in the field of vegetative pharmacology but also concerning influence on psychic functions in man. The possibility should, therefore, be considered that an increased excitatory state of sympathetic centres by LSD 25 is a main factor in the pathogenesis of the well-known psychic disturbances produced by this amide in man.

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Authors and Affiliations

  1. Pharmakologisches Laboratorium der Sandoz AG., Basel

    E. Rothlin, A. Cerletti, H. Konzett, W. R. Schalch & M. Taeschler

Authors
  1. E. Rothlin
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  2. A. Cerletti
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  3. H. Konzett
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  4. W. R. Schalch
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  5. M. Taeschler
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Rothlin, E., Cerletti, A., Konzett, H. et al. Zentrale vegetative LSD-Effekte. Experientia 12, 154–155 (1956). https://doi.org/10.1007/BF02170610

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  • DOI: https://doi.org/10.1007/BF02170610

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